Fabrication of polymeric nanoparticles of poly(ethylene-co-vinyl acetate) coated with chitosan for pulmonary delivery of carvedilol

ABSTRACT Carvedilol is a drug with low oral bioavailability due to its high first‐pass metabolism. The purpose of the present study was to prepare a mucoadhesive dry powder inhaler of this drug loaded in poly(ethylene‐co‐vinyl acetate)(PEVA) nanoparticles for pulmonary delivery. PEVA nanoparticles w...

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Veröffentlicht in:Journal of applied polymer science 2014-01, Vol.131 (1), p.np-n/a
Hauptverfasser: Varshosaz, Jaleh, Taymouri, Somaih, Hamishehkar, Hamed
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Sprache:eng
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