Alendronate decorated nano hydroxyapatite in mesoporous silica: Cytotoxicity and osteogenic properties

► Hydroxyapatite-modified mesoporous silica materials (MSH) have been developed. ► MSH showed lower cytotoxicity than pure mesoporous silica. ► The osteogenesis of MSCs treated by alendronate (AL) decrodated MSH was evaluated. ► The osteogenesis of MSCs induced by MSH-AL is comparable to that induce...

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Veröffentlicht in:	Applied surface science 2011-09, Vol.257 (23), p.9757-9761
Hauptverfasser:	Huang, Wei, Liu, Weiqiang, She, Zhending, Wu, Hongkai, Shi, Xuetao
Format:	Artikel
Sprache:	eng
Schlagworte:	Alendronate Biocompatibility Biomedical materials Bones Bursting Condensed matter: electronic structure, electrical, magnetic, and optical properties Condensed matter: structure, mechanical and thermal properties Cross-disciplinary physics: materials science rheology Cytotoxicity Exact sciences and technology Hydroxyapatite Mesoporous silica Nanostructure Osteogenesis Physics Silicon dioxide Surgical implants
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