Effect of swirling flow on platelet concentration distribution in small-caliber artificial grafts and end-to-end anastomoses
Platelet concentration near the blood vessel wall is one of the major factors in the adhesion of platelets to the wall.In our previous studies,it was found that swirling flows could suppress platelet adhesion in small-caliber artificial grafts and end-to-end anastomoses.In order to better understand...
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| Veröffentlicht in: | Acta mechanica Sinica 2011-10, Vol.27 (5), p.833-839 |
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| creator | Zhan, Fan Fan, Yu-Bo Deng, Xiao-Yan |
| description | Platelet concentration near the blood vessel wall is one of the major factors in the adhesion of platelets to the wall.In our previous studies,it was found that swirling flows could suppress platelet adhesion in small-caliber artificial grafts and end-to-end anastomoses.In order to better understand the beneficial effect of the swirling flow,we numerically analyzed the near-wall concentration distribution of platelets in a straight tube and a sudden tubular expansion tube under both swirling flow and normal flow conditions.The numerical models were created based on our previous experimental studies.The simulation results revealed that when compared with the normal flow,the swirling flow could significantly reduce the near-wall concentration of platelets in both the straight tube and the expansion tube.The present numerical study therefore indicates that the reduction in platelet adhesion under swirling flow conditions in small-caliber arterial grafts,or in end-to-end anastomoses as observed in our previous experimental study,was possibly through a mechanism of platelet transport,in which the swirling flow reduced the near-wall concentration of platelets. |
| doi_str_mv | 10.1007/s10409-011-0486-0 |
| format | Article |
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Fan, Yu-Bo ; Deng, Xiao-Yan</creator><creatorcontrib>Zhan, Fan ; Fan, Yu-Bo ; Deng, Xiao-Yan</creatorcontrib><description>Platelet concentration near the blood vessel wall is one of the major factors in the adhesion of platelets to the wall.In our previous studies,it was found that swirling flows could suppress platelet adhesion in small-caliber artificial grafts and end-to-end anastomoses.In order to better understand the beneficial effect of the swirling flow,we numerically analyzed the near-wall concentration distribution of platelets in a straight tube and a sudden tubular expansion tube under both swirling flow and normal flow conditions.The numerical models were created based on our previous experimental studies.The simulation results revealed that when compared with the normal flow,the swirling flow could significantly reduce the near-wall concentration of platelets in both the straight tube and the expansion tube.The present numerical study therefore indicates that the reduction in platelet adhesion under swirling flow conditions in small-caliber arterial grafts,or in end-to-end anastomoses as observed in our previous experimental study,was possibly through a mechanism of platelet transport,in which the swirling flow reduced the near-wall concentration of platelets.</description><identifier>ISSN: 0567-7718</identifier><identifier>EISSN: 1614-3116</identifier><identifier>DOI: 10.1007/s10409-011-0486-0</identifier><language>eng</language><publisher>Heidelberg: The Chinese Society of Theoretical and Applied Mechanics; Institute of Mechanics, Chinese Academy of Sciences</publisher><subject>Adhesion ; Blood vessels ; Classical and Continuum Physics ; Computational Intelligence ; Engineering ; Engineering Fluid Dynamics ; Expansion tubes ; Grafts ; Mathematical models ; Platelets ; Research Paper ; Swirling ; Theoretical and Applied Mechanics ; Tubes ; 人工移植 ; 小口径 ; 数值分析 ; 旋流 ; 流动条件 ; 浓度分布 ; 终端 ; 血小板粘附</subject><ispartof>Acta mechanica Sinica, 2011-10, Vol.27 (5), p.833-839</ispartof><rights>The Chinese Society of Theoretical and Applied Mechanics; Institute of Mechanics, Chinese Academy of Sciences and Springer-Verlag Berlin Heidelberg 2011</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c347t-34ad06102cf5bb193160ded8bec78759cdf54f308206d9fb960cd2ec95d40f643</citedby><cites>FETCH-LOGICAL-c347t-34ad06102cf5bb193160ded8bec78759cdf54f308206d9fb960cd2ec95d40f643</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Uhttp://image.cqvip.com/vip1000/qk/86601X/86601X.jpg</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10409-011-0486-0$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s10409-011-0486-0$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids></links><search><creatorcontrib>Zhan, Fan</creatorcontrib><creatorcontrib>Fan, Yu-Bo</creatorcontrib><creatorcontrib>Deng, Xiao-Yan</creatorcontrib><title>Effect of swirling flow on platelet concentration distribution in small-caliber artificial grafts and end-to-end anastomoses</title><title>Acta mechanica Sinica</title><addtitle>Acta Mech Sin</addtitle><addtitle>Acta Mechanica Sinica</addtitle><description>Platelet concentration near the blood vessel wall is one of the major factors in the adhesion of platelets to the wall.In our previous studies,it was found that swirling flows could suppress platelet adhesion in small-caliber artificial grafts and end-to-end anastomoses.In order to better understand the beneficial effect of the swirling flow,we numerically analyzed the near-wall concentration distribution of platelets in a straight tube and a sudden tubular expansion tube under both swirling flow and normal flow conditions.The numerical models were created based on our previous experimental studies.The simulation results revealed that when compared with the normal flow,the swirling flow could significantly reduce the near-wall concentration of platelets in both the straight tube and the expansion tube.The present numerical study therefore indicates that the reduction in platelet adhesion under swirling flow conditions in small-caliber arterial grafts,or in end-to-end anastomoses as observed in our previous experimental study,was possibly through a mechanism of platelet transport,in which the swirling flow reduced the near-wall concentration of platelets.</description><subject>Adhesion</subject><subject>Blood vessels</subject><subject>Classical and Continuum Physics</subject><subject>Computational Intelligence</subject><subject>Engineering</subject><subject>Engineering Fluid Dynamics</subject><subject>Expansion tubes</subject><subject>Grafts</subject><subject>Mathematical models</subject><subject>Platelets</subject><subject>Research Paper</subject><subject>Swirling</subject><subject>Theoretical and Applied Mechanics</subject><subject>Tubes</subject><subject>人工移植</subject><subject>小口径</subject><subject>数值分析</subject><subject>旋流</subject><subject>流动条件</subject><subject>浓度分布</subject><subject>终端</subject><subject>血小板粘附</subject><issn>0567-7718</issn><issn>1614-3116</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><recordid>eNp9kE9rVTEQxYMo-Kx-AHdx5yZ25iY3uXcppVah0I2uQ27-PFPyktckjyL44U19xaWrwxnOmWF-hLxH-IQA6rIhCFgZIDIQi2TwguxQomAcUb4kO5ilYkrh8pq8ae0egEtUuCO_r0PwttMSaHuMNcW8pyGVR1oyPSbTffKd2pKtz72aHsfYxdZr3E5_Tcy0HUxKzJoUN1-pqT2GaKNJdF9N6I2a7KjPjvXChgxrWi-H0nx7S14Fk5p_96wX5MeX6-9XX9nt3c23q8-3zHKhOuPCOJAIkw3ztuHKUYLzbtm8VYuaV-vCLAKHZQLp1rCtEqybvF1nJyBIwS_Ix_PeYy0PJ9-6PsRmfUom-3JqGqVCLnBd5YjiOWpraa36oI81Hkz9pRH0E2l9Jq0Haf1EWsPoTOdOG9m891Xfl1PN46P_lj48H_pZ8v5h9P5d4uuCXKmJ_wF6vI66</recordid><startdate>20111001</startdate><enddate>20111001</enddate><creator>Zhan, Fan</creator><creator>Fan, Yu-Bo</creator><creator>Deng, Xiao-Yan</creator><general>The Chinese Society of Theoretical and Applied Mechanics; 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Institute of Mechanics, Chinese Academy of Sciences</pub><doi>10.1007/s10409-011-0486-0</doi><tpages>7</tpages></addata></record> |
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| ispartof | Acta mechanica Sinica, 2011-10, Vol.27 (5), p.833-839 |
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| source | Alma/SFX Local Collection; SpringerLink Journals - AutoHoldings |
| subjects | Adhesion Blood vessels Classical and Continuum Physics Computational Intelligence Engineering Engineering Fluid Dynamics Expansion tubes Grafts Mathematical models Platelets Research Paper Swirling Theoretical and Applied Mechanics Tubes 人工移植 小口径 数值分析 旋流 流动条件 浓度分布 终端 血小板粘附 |
| title | Effect of swirling flow on platelet concentration distribution in small-caliber artificial grafts and end-to-end anastomoses |
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