Helical pinhole SPECT for small-animal imaging: a method for addressing sampling completeness
Pinhole collimators are widely used to image small organs and small animals because sensitivity and resolution improve as the distance between the aperture and the object decreases. Axial blurring is present in reconstruction of SPECT projection data when pinhole apertures follow a circular orbit be...
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| Veröffentlicht in: | IEEE transactions on nuclear science 2003-10, Vol.50 (5), p.1575-1583 |
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| creator | Metzler, S.D. Greer, K.L. Jaszczak, R.J. |
| description | Pinhole collimators are widely used to image small organs and small animals because sensitivity and resolution improve as the distance between the aperture and the object decreases. Axial blurring is present in reconstruction of SPECT projection data when pinhole apertures follow a circular orbit because the object is incompletely sampled. For an object with constant axial extent, the blurring worsens as the radius of rotation (ROR) decreases. In contrast, helical orbits of pinhole collimators can give complete sampling at small ROR, where sensitivity and resolution are improved. Herein, a metric of sampling completeness is introduced. It is used to evaluate the sampling of an object as a function of ROR, axial position, and radial position for circular orbits. The metric is also used to determine the completely sampled volume for a helical orbit of a pinhole aperture. Experimental and computer-simulated projections of circular orbits and helical orbits are reconstructed, yielding similar results; helical orbits reduce axial blurring because of their sampling properties. |
| doi_str_mv | 10.1109/TNS.2003.817948 |
| format | Article |
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Axial blurring is present in reconstruction of SPECT projection data when pinhole apertures follow a circular orbit because the object is incompletely sampled. For an object with constant axial extent, the blurring worsens as the radius of rotation (ROR) decreases. In contrast, helical orbits of pinhole collimators can give complete sampling at small ROR, where sensitivity and resolution are improved. Herein, a metric of sampling completeness is introduced. It is used to evaluate the sampling of an object as a function of ROR, axial position, and radial position for circular orbits. The metric is also used to determine the completely sampled volume for a helical orbit of a pinhole aperture. 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Axial blurring is present in reconstruction of SPECT projection data when pinhole apertures follow a circular orbit because the object is incompletely sampled. For an object with constant axial extent, the blurring worsens as the radius of rotation (ROR) decreases. In contrast, helical orbits of pinhole collimators can give complete sampling at small ROR, where sensitivity and resolution are improved. Herein, a metric of sampling completeness is introduced. It is used to evaluate the sampling of an object as a function of ROR, axial position, and radial position for circular orbits. The metric is also used to determine the completely sampled volume for a helical orbit of a pinhole aperture. Experimental and computer-simulated projections of circular orbits and helical orbits are reconstructed, yielding similar results; helical orbits reduce axial blurring because of their sampling properties.</description><subject>Animals</subject><subject>Apertures</subject><subject>Biomedical engineering</subject><subject>Biomedical imaging</subject><subject>Blurring</subject><subject>Circular orbits</subject><subject>Collimators</subject><subject>Computed tomography</subject><subject>Helical</subject><subject>Image reconstruction</subject><subject>Image sampling</subject><subject>Orbits</subject><subject>Pinholes</subject><subject>Projection</subject><subject>Sampling</subject><subject>Sampling methods</subject><subject>Single photon emission computed tomography</subject><issn>0018-9499</issn><issn>1558-1578</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>RIE</sourceid><recordid>eNp9kUFLAzEQhYMoWKtnD14WD-Jl20w22STepFQrFBVajxLS7Gy7Jd2tm-3Bf29qBcGDl3kzzDcDM4-QS6ADAKqH8-fZgFGaDRRIzdUR6YEQKgUh1THpUQoq1VzrU3IWwjqWXFDRI-8T9JWzPtlW9arxmMxex6N5UjZtEjbW-9TWVdQkhmVVL-8Sm2ywWzXFN2KLosUQYiMJdrP1-8Q1McEO69g4Jyel9QEvfrRP3h7G89Eknb48Po3up6njkHdpsdBa8dKVzC0s5pyjs7KQ0koQaLWmwJhcaLEQvJSoXQlYqBJyqXQUyrI-uTns3bbNxw5DZzZVcOi9rbHZBcNUBnnGIIK3_4JxJzCRC9ij13_QdbNr63iG0YwxxSmVERoeINc2IbRYmm0bX9V-GqBmb4uJtpi9LeZgS5y4OkxUiPhLsyzXuc6-APvriHA</recordid><startdate>20031001</startdate><enddate>20031001</enddate><creator>Metzler, S.D.</creator><creator>Greer, K.L.</creator><creator>Jaszczak, R.J.</creator><general>IEEE</general><general>The Institute of Electrical and Electronics Engineers, Inc. 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Axial blurring is present in reconstruction of SPECT projection data when pinhole apertures follow a circular orbit because the object is incompletely sampled. For an object with constant axial extent, the blurring worsens as the radius of rotation (ROR) decreases. In contrast, helical orbits of pinhole collimators can give complete sampling at small ROR, where sensitivity and resolution are improved. Herein, a metric of sampling completeness is introduced. It is used to evaluate the sampling of an object as a function of ROR, axial position, and radial position for circular orbits. The metric is also used to determine the completely sampled volume for a helical orbit of a pinhole aperture. 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| subjects | Animals Apertures Biomedical engineering Biomedical imaging Blurring Circular orbits Collimators Computed tomography Helical Image reconstruction Image sampling Orbits Pinholes Projection Sampling Sampling methods Single photon emission computed tomography |
| title | Helical pinhole SPECT for small-animal imaging: a method for addressing sampling completeness |
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