Rapakinin, an anti-hypertensive peptide derived from rapeseed protein, dilates mesenteric artery of spontaneously hypertensive rats via the prostaglandin IP receptor followed by CCK sub(1) receptor

The anti-hypertensive peptide Arg-Ile-Tyr, which was isolated based on its inhibitory activity (IC sub(50) = 28 mu M) for angiotensin I-converting enzyme (ACE) from the subtilisin digest of rapeseed protein, exhibited vasorelaxing activity (EC sub(50) = 5.1 mu M) in an endothelium-dependent manner i...

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Veröffentlicht in:	Peptides (New York, N.Y. : 1980) N.Y. : 1980), 2010-05, Vol.31 (5), p.909-914
Hauptverfasser:	Yamada, Yuko, Iwasaki, Masashi, Usui, Hachiro, Ohinata, Kousaku, Marczak, Ewa D, Lipkowski, Andrzej W, Yoshikawa, Masaaki
Format:	Artikel
Sprache:	eng
Schlagworte:	Blocking Inhibitors IP (Internet Protocol) Peptides Proteins Rapeseed Rats Receptors
Online-Zugang:	Volltext
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