Data-Dependent Neutral Gain MS super(3): Toward Automated Identification of the N-Oxide Functional Group in Drug Metabolites

We report here an automated method for the identification of N-oxide functional groups in drug metabolites by using the combination of liquid chromatography/tandem mass spectrometry (LC/MS super()n based on ion-molecule reactions and collision-activated dissociation (CAD). Data-dependent acquisition...

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Veröffentlicht in:	Journal of the American Society for Mass Spectrometry 2010-04, Vol.21 (4), p.559-563
Hauptverfasser:	Habicht, Steven C, Vinueza, Nelson R, Duan, Penggao, Fu, Mingkun, Kenttaemaa, Hilkka I
Format:	Artikel
Sprache:	eng
Schlagworte:	Automated Computer aided design Drugs Functional groups Gain Mass spectrometry Metabolites Pharmaceuticals
Online-Zugang:	Volltext
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