Quantification of in vitro mesenchymal stem cell invasion into tumor spheroids using selective plane illumination microscopy

Mesenchymal stem cell (MSC) homing and integration into tumors are under evaluation for clinical application. This approach requires the identification of conditions for optimal tumor invasion. We describe a tool for the in vitro comparison of parameters influencing invasion. Human MSC added to expe...

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Veröffentlicht in:	Journal of biomedical optics 2015-04, Vol.20 (4), p.040501-040501
Hauptverfasser:	Rühland, Svenja, Wechselberger, Alexandra, Spitzweg, Christine, Huss, Ralf, Nelson, Peter J, Harz, Hartmann
Format:	Artikel
Sprache:	eng
Schlagworte:	Carcinoma, Hepatocellular - pathology Cell Line, Tumor Cell Movement Cell Tracking - methods Humans Lighting - methods Mesenchymal Stromal Cells - pathology Microscopy - methods Neoplasm Invasiveness Spheroids, Cellular - pathology
Online-Zugang:	Volltext
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