Progression of conjunctival primary acquired melanosis (PAM) to widely spreaded malignant melanoma
Primary acquired melanosis (PAM) is an acquired pigmentation of the conjunctival epithelium, a preinvasive pigmented lesion. When it is associated with cellular atypia it can lead to the developement of melanoma. We report a case report of malignant melanoma of the conjuntiva, which arrised from the...
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| Veröffentlicht in: | Collegium antropologicum 2014-12, Vol.38 (4), p.1187-1190 |
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| container_title | Collegium antropologicum |
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| creator | Jandroković, Sonja Popović-Suić, Smiljka Mandić, Jelena Juri Kuzman, Tomislav Skegro, Ivan Kutija, Marija Barisić Masnec, Sanja Kalauz, Miro |
| description | Primary acquired melanosis (PAM) is an acquired pigmentation of the conjunctival epithelium, a preinvasive pigmented lesion. When it is associated with cellular atypia it can lead to the developement of melanoma. We report a case report of malignant melanoma of the conjuntiva, which arrised from the conjuntival PAM. The disease was too extensive for ocular conservation, therefore exenteration was performed. This case highlights the need for regular follow-up of patients with melanocytic lesions of the ocular adnexa, and particular attention to the surgical technique, and careful follow-up to detect further disease activity. |
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When it is associated with cellular atypia it can lead to the developement of melanoma. We report a case report of malignant melanoma of the conjuntiva, which arrised from the conjuntival PAM. The disease was too extensive for ocular conservation, therefore exenteration was performed. This case highlights the need for regular follow-up of patients with melanocytic lesions of the ocular adnexa, and particular attention to the surgical technique, and careful follow-up to detect further disease activity.</description><identifier>ISSN: 0350-6134</identifier><identifier>PMID: 25842754</identifier><language>eng</language><publisher>Croatia</publisher><subject>Aged ; Cancer ; Conjunctival Neoplasms - pathology ; Conjunctival Neoplasms - surgery ; Disease Progression ; Diseases ; Female ; Humans ; Melanoma - diagnosis ; Melanoma - pathology ; Melanoma - surgery ; Melanosis - pathology ; Patients ; Skin pigmentation</subject><ispartof>Collegium antropologicum, 2014-12, Vol.38 (4), p.1187-1190</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25842754$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jandroković, Sonja</creatorcontrib><creatorcontrib>Popović-Suić, Smiljka</creatorcontrib><creatorcontrib>Mandić, Jelena Juri</creatorcontrib><creatorcontrib>Kuzman, Tomislav</creatorcontrib><creatorcontrib>Skegro, Ivan</creatorcontrib><creatorcontrib>Kutija, Marija Barisić</creatorcontrib><creatorcontrib>Masnec, Sanja</creatorcontrib><creatorcontrib>Kalauz, Miro</creatorcontrib><title>Progression of conjunctival primary acquired melanosis (PAM) to widely spreaded malignant melanoma</title><title>Collegium antropologicum</title><addtitle>Coll Antropol</addtitle><description>Primary acquired melanosis (PAM) is an acquired pigmentation of the conjunctival epithelium, a preinvasive pigmented lesion. When it is associated with cellular atypia it can lead to the developement of melanoma. We report a case report of malignant melanoma of the conjuntiva, which arrised from the conjuntival PAM. The disease was too extensive for ocular conservation, therefore exenteration was performed. This case highlights the need for regular follow-up of patients with melanocytic lesions of the ocular adnexa, and particular attention to the surgical technique, and careful follow-up to detect further disease activity.</description><subject>Aged</subject><subject>Cancer</subject><subject>Conjunctival Neoplasms - pathology</subject><subject>Conjunctival Neoplasms - surgery</subject><subject>Disease Progression</subject><subject>Diseases</subject><subject>Female</subject><subject>Humans</subject><subject>Melanoma - diagnosis</subject><subject>Melanoma - pathology</subject><subject>Melanoma - surgery</subject><subject>Melanosis - pathology</subject><subject>Patients</subject><subject>Skin pigmentation</subject><issn>0350-6134</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqN0LtOwzAYBWAPIFoKr4A8lqGSnfg6VhU3qYgOMEe_L6lcJXFqJ6C-PUWEneksn46OzgWak5KTlaAlm6HrnA-EcCmIuEKzgitWSM7myOxS3Cefc4gdjjW2sTuMnR3CJzS4T6GFdMJgj2NI3uHWN9DFHDJe7tav93iI-Cs435xw7pMH90OgCfsOumHCLdygyxqa7G-nXKCPx4f3zfNq-_b0sllvVz3leljVzhZGcAZ1IU3hqACrpREgqK85lExpr5gxUCvCCi81OCslt9RoRam1tlyg5W9vn-Jx9Hmo2pCtb84rfBxzRYWkBVWaqn9QUWpSKsrP9G6io2m9q6ZPqr8Ly29GZm2o</recordid><startdate>201412</startdate><enddate>201412</enddate><creator>Jandroković, Sonja</creator><creator>Popović-Suić, Smiljka</creator><creator>Mandić, Jelena Juri</creator><creator>Kuzman, Tomislav</creator><creator>Skegro, Ivan</creator><creator>Kutija, Marija Barisić</creator><creator>Masnec, Sanja</creator><creator>Kalauz, Miro</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>8BJ</scope><scope>FQK</scope><scope>JBE</scope><scope>7X8</scope></search><sort><creationdate>201412</creationdate><title>Progression of conjunctival primary acquired melanosis (PAM) to widely spreaded malignant melanoma</title><author>Jandroković, Sonja ; Popović-Suić, Smiljka ; Mandić, Jelena Juri ; Kuzman, Tomislav ; Skegro, Ivan ; Kutija, Marija Barisić ; Masnec, Sanja ; Kalauz, Miro</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p159t-fdc2b654af27b2d16ac97b6a61ef5a3489e84bbaf8042e79adc775c1b9811ccc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Aged</topic><topic>Cancer</topic><topic>Conjunctival Neoplasms - pathology</topic><topic>Conjunctival Neoplasms - surgery</topic><topic>Disease Progression</topic><topic>Diseases</topic><topic>Female</topic><topic>Humans</topic><topic>Melanoma - diagnosis</topic><topic>Melanoma - pathology</topic><topic>Melanoma - surgery</topic><topic>Melanosis - pathology</topic><topic>Patients</topic><topic>Skin pigmentation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jandroković, Sonja</creatorcontrib><creatorcontrib>Popović-Suić, Smiljka</creatorcontrib><creatorcontrib>Mandić, Jelena Juri</creatorcontrib><creatorcontrib>Kuzman, Tomislav</creatorcontrib><creatorcontrib>Skegro, Ivan</creatorcontrib><creatorcontrib>Kutija, Marija Barisić</creatorcontrib><creatorcontrib>Masnec, Sanja</creatorcontrib><creatorcontrib>Kalauz, Miro</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>International Bibliography of the Social Sciences (IBSS)</collection><collection>International Bibliography of the Social Sciences</collection><collection>International Bibliography of the Social Sciences</collection><collection>MEDLINE - Academic</collection><jtitle>Collegium antropologicum</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jandroković, Sonja</au><au>Popović-Suić, Smiljka</au><au>Mandić, Jelena Juri</au><au>Kuzman, Tomislav</au><au>Skegro, Ivan</au><au>Kutija, Marija Barisić</au><au>Masnec, Sanja</au><au>Kalauz, Miro</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Progression of conjunctival primary acquired melanosis (PAM) to widely spreaded malignant melanoma</atitle><jtitle>Collegium antropologicum</jtitle><addtitle>Coll Antropol</addtitle><date>2014-12</date><risdate>2014</risdate><volume>38</volume><issue>4</issue><spage>1187</spage><epage>1190</epage><pages>1187-1190</pages><issn>0350-6134</issn><abstract>Primary acquired melanosis (PAM) is an acquired pigmentation of the conjunctival epithelium, a preinvasive pigmented lesion. 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| ispartof | Collegium antropologicum, 2014-12, Vol.38 (4), p.1187-1190 |
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| language | eng |
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| subjects | Aged Cancer Conjunctival Neoplasms - pathology Conjunctival Neoplasms - surgery Disease Progression Diseases Female Humans Melanoma - diagnosis Melanoma - pathology Melanoma - surgery Melanosis - pathology Patients Skin pigmentation |
| title | Progression of conjunctival primary acquired melanosis (PAM) to widely spreaded malignant melanoma |
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