Low-cost thermotherapy for cutaneous leishmaniasis in Sindh, Pakistan
To study the efficacy of a low-cost heating pack device used for thermotherapy in the treatment of cutaneous leishmaniasis. The study was conducted at the Department of Dermatology, Civil Hospital Sukkur, Pakistan, from April 20, 2012, to January 3, 2013. Thermotherapy with Hand-Held Exothermic Crys...
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| Veröffentlicht in: | Journal of the Pakistan Medical Association 2014-12, Vol.64 (12), p.1398-1404 |
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| container_title | Journal of the Pakistan Medical Association |
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| creator | Shah, Sharaf Ali Memon, Abdul Aziz Auwj-e-Shamim Baqi, Shehla Witzig, Richard |
| description | To study the efficacy of a low-cost heating pack device used for thermotherapy in the treatment of cutaneous leishmaniasis.
The study was conducted at the Department of Dermatology, Civil Hospital Sukkur, Pakistan, from April 20, 2012, to January 3, 2013. Thermotherapy with Hand-Held Exothermic Crystallisation Therapy for cutaneous leishmaniasis was performed on each lesion of the participating subjects at an average initial temperature of 51.6°C for 3 minutes daily for 7 days. Patients were followed regularly for 6 months after the therapy. SPSS 20 was used for statistical analysis.
Even though all 27 patients completed 1 week of thermotherapy, only 23(85.2%) patients could be evaluated for full treatment response since 4(14.8%) were lost to complete follow-up. By the final 180-day evaluation, 19 (83%) patients had been cured. Applications were well tolerated with no side effects.
The devise was a convenient, safe, non-toxic and effective treatment for cutaneous leishmaniasis at a fraction of the cost of standard antimonial treatment. Further studies are needed to certify its safety and efficacy as monotherapy for the condition. |
| format | Article |
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The study was conducted at the Department of Dermatology, Civil Hospital Sukkur, Pakistan, from April 20, 2012, to January 3, 2013. Thermotherapy with Hand-Held Exothermic Crystallisation Therapy for cutaneous leishmaniasis was performed on each lesion of the participating subjects at an average initial temperature of 51.6°C for 3 minutes daily for 7 days. Patients were followed regularly for 6 months after the therapy. SPSS 20 was used for statistical analysis.
Even though all 27 patients completed 1 week of thermotherapy, only 23(85.2%) patients could be evaluated for full treatment response since 4(14.8%) were lost to complete follow-up. By the final 180-day evaluation, 19 (83%) patients had been cured. Applications were well tolerated with no side effects.
The devise was a convenient, safe, non-toxic and effective treatment for cutaneous leishmaniasis at a fraction of the cost of standard antimonial treatment. Further studies are needed to certify its safety and efficacy as monotherapy for the condition.</description><identifier>ISSN: 0030-9982</identifier><identifier>PMID: 25842586</identifier><language>eng</language><publisher>Pakistan: Knowledge Bylanes</publisher><subject>Adolescent ; Adult ; Child ; Child, Preschool ; Costs and Cost Analysis ; Economic aspects ; Female ; Humans ; Hyperthermia, Induced - economics ; Hyperthermia, Induced - instrumentation ; Hyperthermia, Induced - methods ; Infant ; Leishmaniasis, Cutaneous ; Leishmaniasis, Cutaneous - economics ; Leishmaniasis, Cutaneous - therapy ; Male ; Middle Aged ; Pakistan ; Parasitic diseases ; Pilot Projects ; Young Adult</subject><ispartof>Journal of the Pakistan Medical Association, 2014-12, Vol.64 (12), p.1398-1404</ispartof><rights>COPYRIGHT 2014 Knowledge Bylanes</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25842586$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Shah, Sharaf Ali</creatorcontrib><creatorcontrib>Memon, Abdul Aziz</creatorcontrib><creatorcontrib>Auwj-e-Shamim</creatorcontrib><creatorcontrib>Baqi, Shehla</creatorcontrib><creatorcontrib>Witzig, Richard</creatorcontrib><title>Low-cost thermotherapy for cutaneous leishmaniasis in Sindh, Pakistan</title><title>Journal of the Pakistan Medical Association</title><addtitle>J Pak Med Assoc</addtitle><description>To study the efficacy of a low-cost heating pack device used for thermotherapy in the treatment of cutaneous leishmaniasis.
The study was conducted at the Department of Dermatology, Civil Hospital Sukkur, Pakistan, from April 20, 2012, to January 3, 2013. Thermotherapy with Hand-Held Exothermic Crystallisation Therapy for cutaneous leishmaniasis was performed on each lesion of the participating subjects at an average initial temperature of 51.6°C for 3 minutes daily for 7 days. Patients were followed regularly for 6 months after the therapy. SPSS 20 was used for statistical analysis.
Even though all 27 patients completed 1 week of thermotherapy, only 23(85.2%) patients could be evaluated for full treatment response since 4(14.8%) were lost to complete follow-up. By the final 180-day evaluation, 19 (83%) patients had been cured. Applications were well tolerated with no side effects.
The devise was a convenient, safe, non-toxic and effective treatment for cutaneous leishmaniasis at a fraction of the cost of standard antimonial treatment. Further studies are needed to certify its safety and efficacy as monotherapy for the condition.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Costs and Cost Analysis</subject><subject>Economic aspects</subject><subject>Female</subject><subject>Humans</subject><subject>Hyperthermia, Induced - economics</subject><subject>Hyperthermia, Induced - instrumentation</subject><subject>Hyperthermia, Induced - methods</subject><subject>Infant</subject><subject>Leishmaniasis, Cutaneous</subject><subject>Leishmaniasis, Cutaneous - economics</subject><subject>Leishmaniasis, Cutaneous - therapy</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Pakistan</subject><subject>Parasitic diseases</subject><subject>Pilot Projects</subject><subject>Young Adult</subject><issn>0030-9982</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkF9LwzAUxfuguDn9ClIQxAcr-dOkyeMYmwoDBfW53DXJGk2b2aTIvr0dm-BALvdeuPzO4XBPkjFCFGVSCjJKzkP4QIhwhtBZMiJM5EPzcTJf-u-s8iGmsdZd43cTNtvU-C6t-git9n1InbahbqC1EGxIbZu-2lbVd-kLfNowQBfJqQEX9OVhT5L3xfxt9pgtnx-eZtNltqZIxgxXgmEupcJaSWI4xwYUYVjlAjOVg1FGgVaGrATXCAq2YpShSkiCJCMFo5Pkdu-76fxXr0MsGxsq7dw-Z4l5gQkWgucDer1H1-B0aVvjYwfVDi-nVBJRSEzoQN3_Qw2ldGMr32pjh_uR4OaPoNbgYh2866P1bTgGrw5R-1WjVbnpbAPdtvx9Pf0B6NR8Tw</recordid><startdate>20141201</startdate><enddate>20141201</enddate><creator>Shah, Sharaf Ali</creator><creator>Memon, Abdul Aziz</creator><creator>Auwj-e-Shamim</creator><creator>Baqi, Shehla</creator><creator>Witzig, Richard</creator><general>Knowledge Bylanes</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>20141201</creationdate><title>Low-cost thermotherapy for cutaneous leishmaniasis in Sindh, Pakistan</title><author>Shah, Sharaf Ali ; Memon, Abdul Aziz ; Auwj-e-Shamim ; Baqi, Shehla ; Witzig, Richard</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-g309t-1c851699d1ed92f661fad251d4815d4afdfdaedf2b86e0a75b5350c8920952753</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Costs and Cost Analysis</topic><topic>Economic aspects</topic><topic>Female</topic><topic>Humans</topic><topic>Hyperthermia, Induced - economics</topic><topic>Hyperthermia, Induced - instrumentation</topic><topic>Hyperthermia, Induced - methods</topic><topic>Infant</topic><topic>Leishmaniasis, Cutaneous</topic><topic>Leishmaniasis, Cutaneous - economics</topic><topic>Leishmaniasis, Cutaneous - therapy</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Pakistan</topic><topic>Parasitic diseases</topic><topic>Pilot Projects</topic><topic>Young Adult</topic><toplevel>online_resources</toplevel><creatorcontrib>Shah, Sharaf Ali</creatorcontrib><creatorcontrib>Memon, Abdul Aziz</creatorcontrib><creatorcontrib>Auwj-e-Shamim</creatorcontrib><creatorcontrib>Baqi, Shehla</creatorcontrib><creatorcontrib>Witzig, Richard</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of the Pakistan Medical Association</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Shah, Sharaf Ali</au><au>Memon, Abdul Aziz</au><au>Auwj-e-Shamim</au><au>Baqi, Shehla</au><au>Witzig, Richard</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Low-cost thermotherapy for cutaneous leishmaniasis in Sindh, Pakistan</atitle><jtitle>Journal of the Pakistan Medical Association</jtitle><addtitle>J Pak Med Assoc</addtitle><date>2014-12-01</date><risdate>2014</risdate><volume>64</volume><issue>12</issue><spage>1398</spage><epage>1404</epage><pages>1398-1404</pages><issn>0030-9982</issn><abstract>To study the efficacy of a low-cost heating pack device used for thermotherapy in the treatment of cutaneous leishmaniasis.
The study was conducted at the Department of Dermatology, Civil Hospital Sukkur, Pakistan, from April 20, 2012, to January 3, 2013. Thermotherapy with Hand-Held Exothermic Crystallisation Therapy for cutaneous leishmaniasis was performed on each lesion of the participating subjects at an average initial temperature of 51.6°C for 3 minutes daily for 7 days. Patients were followed regularly for 6 months after the therapy. SPSS 20 was used for statistical analysis.
Even though all 27 patients completed 1 week of thermotherapy, only 23(85.2%) patients could be evaluated for full treatment response since 4(14.8%) were lost to complete follow-up. By the final 180-day evaluation, 19 (83%) patients had been cured. Applications were well tolerated with no side effects.
The devise was a convenient, safe, non-toxic and effective treatment for cutaneous leishmaniasis at a fraction of the cost of standard antimonial treatment. Further studies are needed to certify its safety and efficacy as monotherapy for the condition.</abstract><cop>Pakistan</cop><pub>Knowledge Bylanes</pub><pmid>25842586</pmid><tpages>7</tpages></addata></record> |
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| source | MEDLINE; TestCollectionTL3OpenAccess; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Adolescent Adult Child Child, Preschool Costs and Cost Analysis Economic aspects Female Humans Hyperthermia, Induced - economics Hyperthermia, Induced - instrumentation Hyperthermia, Induced - methods Infant Leishmaniasis, Cutaneous Leishmaniasis, Cutaneous - economics Leishmaniasis, Cutaneous - therapy Male Middle Aged Pakistan Parasitic diseases Pilot Projects Young Adult |
| title | Low-cost thermotherapy for cutaneous leishmaniasis in Sindh, Pakistan |
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