Novel peptides functionally targeting in vivo human lung cancer discovered by in vivo peptide displayed phage screening

Discovery of the cancer-specific peptidic ligands have been emphasized for active targeting drug delivery system and non-invasive imaging. For the discovery of useful and applicable peptidic ligands, in vivo peptide-displayed phage screening has been performed in this study using a xenograft mouse m...

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Veröffentlicht in:	Amino acids 2015-02, Vol.47 (2), p.281-289
Hauptverfasser:	Lee, Kyoung Jin, Lee, Jae Hee, Chung, Hye Kyung, Choi, Jinhyang, Park, Jaesook, Park, Seok Soon, Ju, Eun Jin, Park, Jin, Shin, Seol Hwa, Park, Hye Ji, Ko, Eun Jung, Suh, Nayoung, Kim, InKi, Hwang, Jung Jin, Song, Si Yeol, Jeong, Seong-Yun, Choi, Eun Kyung
Format:	Artikel
Sprache:	eng
Schlagworte:	adenocarcinoma Analytical Chemistry animal models Animals Antineoplastic Agents - chemistry Antineoplastic Agents - pharmacology bacteriophages Biochemical Engineering Biochemistry Biocompatibility Biomedical and Life Sciences Biomedical materials Cancer caudal vein diagnostic techniques DNA libraries Drug Delivery Systems drugs Humans image analysis immunohistochemistry In vivo testing In vivo tests intravenous injection Life Sciences ligands lung neoplasms Lung Neoplasms - drug therapy Lung Neoplasms - metabolism Lung Neoplasms - pathology Lungs Male Mice Mice, Inbred BALB C Mice, Nude neoplasm cells Neurobiology Original Article Peptide Library Peptides Phage Phages Proteomics screening sequence homology Surgical implants Tumor Microenvironment - drug effects Xenograft Model Antitumor Assays
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