Anti-inflammatory and protective effects of 2-methacryloyloxyethyl phosphorylcholine polymer on oral epithelial cells

Periodontitis is a chronic inflammatory disease initiated by a microbial biofilm formed in the periodontal pocket. Gingival epithelium plays important roles as the first physical barrier to bacterial invasion and in orchestrating the innate immune reaction via toll‐like receptors (TLRs), which recog...

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Veröffentlicht in:	Journal of biomedical materials research. Part A 2015-02, Vol.103 (2), p.555-563
Hauptverfasser:	Yumoto, Hiromichi, Hirota, Katsuhiko, Hirao, Kouji, Miyazaki, Tsuyoshi, Yamamoto, Nobuyuki, Miyamoto, Koji, Murakami, Keiji, Fujiwara, Natsumi, Matsuo, Takashi, Miyake, Yoichiro
Format:	Artikel
Sprache:	eng
Schlagworte:	2-Methacryloyloxyethyl phosphorylcholine Anti-Inflammatory Agents - chemistry Anti-Inflammatory Agents - pharmacology Bacteroidaceae Infections - drug therapy Bacteroidaceae Infections - metabolism Bacteroidaceae Infections - pathology Cell Line, Transformed Epithelial Cells - metabolism Epithelial Cells - microbiology Epithelial Cells - pathology Humans interleukin-8 lipopolysaccharide Mouth - metabolism Mouth - microbiology Mouth - pathology oral epithelial cells Periodontitis - drug therapy Periodontitis - metabolism Periodontitis - pathology Phosphorylcholine - analogs & derivatives Phosphorylcholine - chemistry Phosphorylcholine - pharmacology Polymethacrylic Acids - chemistry Polymethacrylic Acids - pharmacology Porphyromonas gingivalis - metabolism toll-like receptor
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