Association of Two Well-defined Polymorphisms in Leptin and Leptin Receptor Genes with Hypertension and Circulating Leptin: A Meta-analysis

Background and Aims The genes encoding adipose-derived hormone leptin and its receptor (LEPR) are increasingly deemed as hypertension-susceptibility genes. In this meta-analysis, we summarized the association of the II/I polymorphism in leptin gene and Gln223Arg polymorphism in LEPR gene with hypert...

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Veröffentlicht in:	Archives of medical research 2015, Vol.46 (1), p.38-46
Hauptverfasser:	Li, Ying-xue, Zhang, Qi, Shang, Xiao-ming, Li, Yong-qiu, Liu, Xiao-kun, Liu, Chang-qing, Liu, Xiao-ming, Zhang, Qing-hua
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Asian Continental Ancestry Group - genetics Essential Hypertension European Continental Ancestry Group - genetics Gene Frequency Genetic Predisposition to Disease Genotype Humans Hypertension Hypertension - genetics Internal Medicine Leptin Leptin - blood Leptin - genetics Leptin receptor Meta-analysis Obesity - genetics Odds Ratio Polymorphism Polymorphism, Single Nucleotide Receptors, Leptin - genetics
Online-Zugang:	Volltext
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