An alternative approach to confidence interval estimation for the win ratio statistic

Pocock et al. (2012, European Heart Journal 33, 176–182) proposed a win ratio approach to analyzing composite endpoints comprised of outcomes with different clinical priorities. In this article, we establish a statistical framework for this approach. We derive the null hypothesis and propose a close...

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Veröffentlicht in:	Biometrics 2015-03, Vol.71 (1), p.139-145
Hauptverfasser:	Luo, Xiaodong, Tian, Hong, Mohanty, Surya, Tsai, Wei Yann
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms BIOMETRIC METHODOLOGY Biometrics Clinical outcomes Clinical trials Composite endpoints Confidence Intervals Data Interpretation, Statistical Factor Xa Inhibitors - therapeutic use Humans Hypothesis testing Odds Ratio Outcome Assessment (Health Care) - methods Reproducibility of Results Risk Assessment - methods Rivaroxaban - therapeutic use Sensitivity and Specificity Statistical Distributions Stroke - mortality Stroke - prevention & control Survival Analysis Treatment Outcome Variance estimation Win ratio
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