Germ line polymorphisms of p53 and CYP1A1 genes involved in human lung cancer

The p53 tumor suppressor gene is mutated in diverse types of human cancer, and the normal allele encodes a nuclear protein that regulates expression of cell cycle-related genes as a transcription factor. The wild-type of p53 protein exists as at least two forms of variants among human populations, a...

Ausführliche Beschreibung