Effects of captopril on cardiovascular reflexes and respiratory mechanisms in rats submitted to monocrotaline-induced pulmonary arterial hypertension

Abstract Background Pulmonary Arterial Hypertension (PAH) is a disease associated with increased arteriolar resistance in the lungs. Due to hypoxemia, some physiological mechanisms can be posteriorly affected, including respiratory and cardiovascular reflexes, but this has not yet been fully investi...

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Veröffentlicht in:	Pulmonary pharmacology & therapeutics 2015-02, Vol.30, p.57-65
Hauptverfasser:	Wittmer, Verônica Lourenço, Waichert, Élio, Gava, Pablo Lúcio, Pereira, Fausto Edmundo Lima, Guimarães, Marco Cesar Cunegundes, de Figueiredo, Suely Gomes, Mauad, Hélder
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin-Converting Enzyme Inhibitors - pharmacology Animals Baroreflex Baroreflex - drug effects Captopril Captopril - pharmacology Chemoreflex Disease Models, Animal Hypertension, Pulmonary - drug therapy Hypertension, Pulmonary - physiopathology Male Medical Education Monocrotaline Monocrotaline - toxicity Pulmonary Arterial Hypertension Pulmonary/Respiratory Rats Rats, Wistar Vascular Remodeling - drug effects
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