Docetaxel Modulates the Delayed Rectifier Potassium Current (IK) and ATP-Sensitive Potassium Current (IKATP) in Human Breast Cancer Cells

Ion channel expression and activity may be affected during tumor development and cancer growth. Activation of potassium (K + ) channels in human breast cancer cells is reported to be involved in cell cycle progression. In this study, we investigated the effects of docetaxel on the delayed rectifier...

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Veröffentlicht in:	The Journal of membrane biology 2015-04, Vol.248 (2), p.197-204
Hauptverfasser:	Sun, Tao, Song, Zhi-Guo, Jiang, Da-Qing, Nie, Hong-Guang, Han, Dong-Yun
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - pharmacology Biochemistry Biomedical and Life Sciences Breast cancer Breast Neoplasms - metabolism Cell Line, Tumor Delayed Rectifier Potassium Channels - metabolism Female Human Physiology Humans Ions KATP Channels - metabolism Life Sciences MCF-7 Cells Membrane Potentials - drug effects Patch-Clamp Techniques Potassium Taxoids - pharmacology
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