Motoneurons destined to die are rescued by blocking n-methyl- d-aspartate receptors by MK-801

Motoneurons to soleus muscle die if their axons are injured at birth. 7,16 We tested the possibility that their death may be caused by toxic effects of excitatory transmitters such as glutamate. Animals that had their sciatic nerves crushed at birth were treated either with a blocker of the N-methyl...

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Veröffentlicht in:Neuroscience 1993-05, Vol.54 (2), p.283-285
Hauptverfasser: Mentis, G.Z., Greensmith, L., Vrbová, G.
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Sprache:eng
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