Transforming growth factor-beta and IL-1 beta act in synergy to enhance IL-6 secretion by the intestinal epithelial cell line, IEC-6

Intestinal epithelial cells are a potentially important source for a number of cytokines that may modulate the immune response at the intestinal mucosa. We have recently begun to study the mechanisms that regulate IL-6 production by intestinal epithelial cells using the nontransformed crypt-like rat...

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Veröffentlicht in:	The Journal of immunology (1950) 1993-07, Vol.151 (2), p.970-978
Hauptverfasser:	McGee, DW, Beagley, KW, Aicher, WK, McGhee, JR
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of the immune response. Humoral and cellular immunity Animals Biological and medical sciences Cell Line Drug Synergism Epithelium - metabolism Fundamental and applied biological sciences. Psychology Fundamental immunology Immunobiology Interleukin-1 - pharmacology Interleukin-6 - genetics Interleukin-6 - secretion Intestinal Mucosa - drug effects Intestinal Mucosa - metabolism Lymphokines, interleukins ( function, expression) Rats Receptors, Interleukin-1 - analysis Regulatory factors and their cellular receptors RNA, Messenger - analysis Transforming Growth Factor beta - pharmacology
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