Foxa2-venus fusion reporter mouse line allows live-cell analysis of endoderm-derived organ formation

The Foxa2‐winged helix/forkhead box transcription factor (TF) is absolutely required for endoderm formation and organogenesis. Foxa2 plays essential roles during lung, liver, pancreas, and gastrointestinal tract development and regulates cell‐type specific programs in the adult organism. To specific...

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Veröffentlicht in:	Genesis (New York, N.Y. : 2000) N.Y. : 2000), 2013-08, Vol.51 (8), p.596-604
Hauptverfasser:	Burtscher, Ingo, Barkey, Wenke, Lickert, Heiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bacterial Proteins - analysis Bacterial Proteins - genetics endoderm Endoderm - cytology Endoderm - metabolism ES cells fluorescent reporter Foxa2 gastrointestinal tract gastrulation Genes, Reporter - genetics Hepatocyte Nuclear Factor 3-beta - genetics Hepatocyte Nuclear Factor 3-beta - metabolism HMGB Proteins - genetics HMGB Proteins - metabolism liver Luminescent Proteins - analysis Luminescent Proteins - genetics lung Mice Mice, Transgenic Microscopy, Fluorescence mouse embryo node notochord Organogenesis pancreas Recombinant Fusion Proteins - genetics Recombinant Fusion Proteins - metabolism Sox17 SOXF Transcription Factors - genetics SOXF Transcription Factors - metabolism
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