Assessment of 2,4-difluoroaniline Aquatic Toxicity Using A Zebrafish (Danio rerio) Model
Bio-monitoring, in the control strategies for pollution, has several advantages over other tests in aquatic organisms. Bio-effects may link the bioavailability of the compounds of interest with their concentration at target organs and intrinsic toxicity. Potential harmful effects of 2,4-difluoroanil...
Gespeichert in:
| Veröffentlicht in: | Wētchasān sattawaphāet 2014-12, Vol.44 (4), p.445-445 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 445 |
|---|---|
| container_issue | 4 |
| container_start_page | 445 |
| container_title | Wētchasān sattawaphāet |
| container_volume | 44 |
| creator | Mosneang, Crina Laura Grozea, Adrian Oprescu, Ion Dumitrescu, Eugenia Muselin, Florin Gál, Dénes Cristina, Romeo T |
| description | Bio-monitoring, in the control strategies for pollution, has several advantages over other tests in aquatic organisms. Bio-effects may link the bioavailability of the compounds of interest with their concentration at target organs and intrinsic toxicity. Potential harmful effects of 2,4-difluoroaniline (DFA), on a 96-hour acute static test, on adult zebrafish (Danio rerio) were followed. According to OECD 203: Fish Acute Toxicity Test, LC50 was determined using 70 adult zebrafish AB strain and 14 zebrafish as control group, to evaluate the effects and action at different concentrations of DFA. Obtained data were analyzed, using Minitab Statistical Software as Goodness-of-Fit correlation tests. Logarithmic value obtained for LC50 was of 2.30311, which corresponded to LC50 of 200.96 mg/L. Results from the performed work reinforce the idea of the zebrafish adults as simple and easy reproducible model organisms in ecotoxicology. The results obtained for LC50, in the authors' opinion, are useful and applicable to a large number of substances, especially in field conditions when overall effectiveness is more important than meticulousness of the method. |
| format | Article |
| fullrecord | <record><control><sourceid>proquest</sourceid><recordid>TN_cdi_proquest_miscellaneous_1668260959</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3575108381</sourcerecordid><originalsourceid>FETCH-LOGICAL-p216t-f630734744489003851fb692e701e09aaa57ff275fe660c4db31c640949467b93</originalsourceid><addsrcrecordid>eNpdzk9LwzAYx_EcFBxz7yHgZYKFJ3-aNMcy_8LEywbiZaTtE83oki1pQd-9FT15-l0-_PiekRkwXhZKGnZBFjnvAYBBKUHwGXmtc8acDxgGGh3lN7LovOvHmKINvvcBaX0a7eBbuomfvvXDF91mH95pTd-wSdb5_EGXtxOONGHy8Zo-xw77S3LubJ9x8bdzsr2_26wei_XLw9OqXhdHztRQOCVAC6mllJUBEFXJXKMMRw0MwVhrS-0c16VDpaCVXSNYqyQYaaTSjRFzsvz9PaZ4GjEPu4PPLfa9DRjHvGNKVVyBKX_o1T-6j2MKU92kpNGGGS7EN4UGWR0</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1649791923</pqid></control><display><type>article</type><title>Assessment of 2,4-difluoroaniline Aquatic Toxicity Using A Zebrafish (Danio rerio) Model</title><source>EZB-FREE-00999 freely available EZB journals</source><creator>Mosneang, Crina Laura ; Grozea, Adrian ; Oprescu, Ion ; Dumitrescu, Eugenia ; Muselin, Florin ; Gál, Dénes ; Cristina, Romeo T</creator><creatorcontrib>Mosneang, Crina Laura ; Grozea, Adrian ; Oprescu, Ion ; Dumitrescu, Eugenia ; Muselin, Florin ; Gál, Dénes ; Cristina, Romeo T</creatorcontrib><description>Bio-monitoring, in the control strategies for pollution, has several advantages over other tests in aquatic organisms. Bio-effects may link the bioavailability of the compounds of interest with their concentration at target organs and intrinsic toxicity. Potential harmful effects of 2,4-difluoroaniline (DFA), on a 96-hour acute static test, on adult zebrafish (Danio rerio) were followed. According to OECD 203: Fish Acute Toxicity Test, LC50 was determined using 70 adult zebrafish AB strain and 14 zebrafish as control group, to evaluate the effects and action at different concentrations of DFA. Obtained data were analyzed, using Minitab Statistical Software as Goodness-of-Fit correlation tests. Logarithmic value obtained for LC50 was of 2.30311, which corresponded to LC50 of 200.96 mg/L. Results from the performed work reinforce the idea of the zebrafish adults as simple and easy reproducible model organisms in ecotoxicology. The results obtained for LC50, in the authors' opinion, are useful and applicable to a large number of substances, especially in field conditions when overall effectiveness is more important than meticulousness of the method.</description><identifier>ISSN: 0125-6491</identifier><language>eng</language><publisher>Bangkok: Chulalongkorn University, Faculty of Veterinary Science</publisher><subject>Animals ; Councils ; Danio rerio ; Disinfection & disinfectants ; Fish ; Freshwater ; Laboratories ; Medical research ; Molecular weight ; Neurosciences ; Studies ; Toxicity ; Values ; Veterinary medicine ; Zebrafish</subject><ispartof>Wētchasān sattawaphāet, 2014-12, Vol.44 (4), p.445-445</ispartof><rights>Copyright Chulalongkorn University, Faculty of Veterinary Science Dec 2014</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids></links><search><creatorcontrib>Mosneang, Crina Laura</creatorcontrib><creatorcontrib>Grozea, Adrian</creatorcontrib><creatorcontrib>Oprescu, Ion</creatorcontrib><creatorcontrib>Dumitrescu, Eugenia</creatorcontrib><creatorcontrib>Muselin, Florin</creatorcontrib><creatorcontrib>Gál, Dénes</creatorcontrib><creatorcontrib>Cristina, Romeo T</creatorcontrib><title>Assessment of 2,4-difluoroaniline Aquatic Toxicity Using A Zebrafish (Danio rerio) Model</title><title>Wētchasān sattawaphāet</title><description>Bio-monitoring, in the control strategies for pollution, has several advantages over other tests in aquatic organisms. Bio-effects may link the bioavailability of the compounds of interest with their concentration at target organs and intrinsic toxicity. Potential harmful effects of 2,4-difluoroaniline (DFA), on a 96-hour acute static test, on adult zebrafish (Danio rerio) were followed. According to OECD 203: Fish Acute Toxicity Test, LC50 was determined using 70 adult zebrafish AB strain and 14 zebrafish as control group, to evaluate the effects and action at different concentrations of DFA. Obtained data were analyzed, using Minitab Statistical Software as Goodness-of-Fit correlation tests. Logarithmic value obtained for LC50 was of 2.30311, which corresponded to LC50 of 200.96 mg/L. Results from the performed work reinforce the idea of the zebrafish adults as simple and easy reproducible model organisms in ecotoxicology. The results obtained for LC50, in the authors' opinion, are useful and applicable to a large number of substances, especially in field conditions when overall effectiveness is more important than meticulousness of the method.</description><subject>Animals</subject><subject>Councils</subject><subject>Danio rerio</subject><subject>Disinfection & disinfectants</subject><subject>Fish</subject><subject>Freshwater</subject><subject>Laboratories</subject><subject>Medical research</subject><subject>Molecular weight</subject><subject>Neurosciences</subject><subject>Studies</subject><subject>Toxicity</subject><subject>Values</subject><subject>Veterinary medicine</subject><subject>Zebrafish</subject><issn>0125-6491</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNpdzk9LwzAYx_EcFBxz7yHgZYKFJ3-aNMcy_8LEywbiZaTtE83oki1pQd-9FT15-l0-_PiekRkwXhZKGnZBFjnvAYBBKUHwGXmtc8acDxgGGh3lN7LovOvHmKINvvcBaX0a7eBbuomfvvXDF91mH95pTd-wSdb5_EGXtxOONGHy8Zo-xw77S3LubJ9x8bdzsr2_26wei_XLw9OqXhdHztRQOCVAC6mllJUBEFXJXKMMRw0MwVhrS-0c16VDpaCVXSNYqyQYaaTSjRFzsvz9PaZ4GjEPu4PPLfa9DRjHvGNKVVyBKX_o1T-6j2MKU92kpNGGGS7EN4UGWR0</recordid><startdate>20141201</startdate><enddate>20141201</enddate><creator>Mosneang, Crina Laura</creator><creator>Grozea, Adrian</creator><creator>Oprescu, Ion</creator><creator>Dumitrescu, Eugenia</creator><creator>Muselin, Florin</creator><creator>Gál, Dénes</creator><creator>Cristina, Romeo T</creator><general>Chulalongkorn University, Faculty of Veterinary Science</general><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>BVBZV</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M2O</scope><scope>M7P</scope><scope>MBDVC</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7TV</scope><scope>C1K</scope><scope>F1W</scope><scope>H95</scope><scope>L.G</scope></search><sort><creationdate>20141201</creationdate><title>Assessment of 2,4-difluoroaniline Aquatic Toxicity Using A Zebrafish (Danio rerio) Model</title><author>Mosneang, Crina Laura ; Grozea, Adrian ; Oprescu, Ion ; Dumitrescu, Eugenia ; Muselin, Florin ; Gál, Dénes ; Cristina, Romeo T</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p216t-f630734744489003851fb692e701e09aaa57ff275fe660c4db31c640949467b93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Animals</topic><topic>Councils</topic><topic>Danio rerio</topic><topic>Disinfection & disinfectants</topic><topic>Fish</topic><topic>Freshwater</topic><topic>Laboratories</topic><topic>Medical research</topic><topic>Molecular weight</topic><topic>Neurosciences</topic><topic>Studies</topic><topic>Toxicity</topic><topic>Values</topic><topic>Veterinary medicine</topic><topic>Zebrafish</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mosneang, Crina Laura</creatorcontrib><creatorcontrib>Grozea, Adrian</creatorcontrib><creatorcontrib>Oprescu, Ion</creatorcontrib><creatorcontrib>Dumitrescu, Eugenia</creatorcontrib><creatorcontrib>Muselin, Florin</creatorcontrib><creatorcontrib>Gál, Dénes</creatorcontrib><creatorcontrib>Cristina, Romeo T</creatorcontrib><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>East & South Asia Database</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Research Library</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>Pollution Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ASFA: Aquatic Sciences and Fisheries Abstracts</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 1: Biological Sciences & Living Resources</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) Professional</collection><jtitle>Wētchasān sattawaphāet</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mosneang, Crina Laura</au><au>Grozea, Adrian</au><au>Oprescu, Ion</au><au>Dumitrescu, Eugenia</au><au>Muselin, Florin</au><au>Gál, Dénes</au><au>Cristina, Romeo T</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Assessment of 2,4-difluoroaniline Aquatic Toxicity Using A Zebrafish (Danio rerio) Model</atitle><jtitle>Wētchasān sattawaphāet</jtitle><date>2014-12-01</date><risdate>2014</risdate><volume>44</volume><issue>4</issue><spage>445</spage><epage>445</epage><pages>445-445</pages><issn>0125-6491</issn><abstract>Bio-monitoring, in the control strategies for pollution, has several advantages over other tests in aquatic organisms. Bio-effects may link the bioavailability of the compounds of interest with their concentration at target organs and intrinsic toxicity. Potential harmful effects of 2,4-difluoroaniline (DFA), on a 96-hour acute static test, on adult zebrafish (Danio rerio) were followed. According to OECD 203: Fish Acute Toxicity Test, LC50 was determined using 70 adult zebrafish AB strain and 14 zebrafish as control group, to evaluate the effects and action at different concentrations of DFA. Obtained data were analyzed, using Minitab Statistical Software as Goodness-of-Fit correlation tests. Logarithmic value obtained for LC50 was of 2.30311, which corresponded to LC50 of 200.96 mg/L. Results from the performed work reinforce the idea of the zebrafish adults as simple and easy reproducible model organisms in ecotoxicology. The results obtained for LC50, in the authors' opinion, are useful and applicable to a large number of substances, especially in field conditions when overall effectiveness is more important than meticulousness of the method.</abstract><cop>Bangkok</cop><pub>Chulalongkorn University, Faculty of Veterinary Science</pub><tpages>1</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0125-6491 |
| ispartof | Wētchasān sattawaphāet, 2014-12, Vol.44 (4), p.445-445 |
| issn | 0125-6491 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1668260959 |
| source | EZB-FREE-00999 freely available EZB journals |
| subjects | Animals Councils Danio rerio Disinfection & disinfectants Fish Freshwater Laboratories Medical research Molecular weight Neurosciences Studies Toxicity Values Veterinary medicine Zebrafish |
| title | Assessment of 2,4-difluoroaniline Aquatic Toxicity Using A Zebrafish (Danio rerio) Model |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-10T10%3A49%3A25IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Assessment%20of%202,4-difluoroaniline%20Aquatic%20Toxicity%20Using%20A%20Zebrafish%20(Danio%20rerio)%20Model&rft.jtitle=W%C4%93tchas%C4%81n%20sattawaph%C4%81et&rft.au=Mosneang,%20Crina%20Laura&rft.date=2014-12-01&rft.volume=44&rft.issue=4&rft.spage=445&rft.epage=445&rft.pages=445-445&rft.issn=0125-6491&rft_id=info:doi/&rft_dat=%3Cproquest%3E3575108381%3C/proquest%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1649791923&rft_id=info:pmid/&rfr_iscdi=true |