IL28B rs12980275 polymorphism shows association with response to treatment in Pakistani patients with Chronic Hepatitis C

The aim of this study was to describe the genetic characteristics of Pakistani patients infected with hepatitis C virus (HCV) in relation to IL28B polymorphisms and its association to interferon and ribavirin treatment response. A total of 220 patients, infected with HCV were enrolled, out of which...

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Veröffentlicht in:	Journal of medical virology 2015-05, Vol.87 (5), p.814-820
Hauptverfasser:	Shaikh, Naila, Waryah, Ali Muhammad, Devrajani, Bikha Ram, Rajput, Muhammad Irfan, Hayat, Atif Sitwat, Shaikh, Samiullah
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antiviral Agents - therapeutic use Epidemiology Female Genetic Variation Genotype HCV Hepatitis Hepatitis C virus Hepatitis C, Chronic - drug therapy Humans IL28B polymorphisms Interferon-alpha - therapeutic use Interferons Interleukins - genetics Male Medical treatment Middle Aged Pakistan Polymerase Chain Reaction Polymorphism Polymorphism, Restriction Fragment Length Ribavirin - therapeutic use Treatment Outcome treatment response Virology
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