Hemichannels: New pathways for gliotransmitter release

Hemichannels: New pathways for gliotransmitter release

Highlights • Glial cell hemichannels can release relevant quantities of gliotransmitters. • Hemichannel opening could be associated with cell death. • Cx26 hemichannel-dependent release of ATP mediates chemoreception. • Cx43 hemichannels participate in brain glucosensing.

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Bibliographische Detailangaben
Veröffentlicht in:Neuroscience 2015-02, Vol.286, p.45-59
Hauptverfasser: Montero, T.D, Orellana, J.A
Format: Artikel
Sprache:eng
Schlagworte:
Adenosine Triphosphate - metabolism
Animals
astrocyte
Brain - secretion
connexin
Connexins - metabolism
Connexins - secretion
hemichannel
Humans
microglia
Neuroglia - metabolism
Neuroglia - secretion
Neurology
neuron
Neurons - secretion
pannexin
Signal Transduction
Synaptic Transmission
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Beschreibung
Zusammenfassung:Highlights • Glial cell hemichannels can release relevant quantities of gliotransmitters. • Hemichannel opening could be associated with cell death. • Cx26 hemichannel-dependent release of ATP mediates chemoreception. • Cx43 hemichannels participate in brain glucosensing.
ISSN:0306-4522
1873-7544
DOI:10.1016/j.neuroscience.2014.11.048