Clinical impact of herpesvirus entry mediator expression in human hepatocellular carcinoma

Abstract Background Herpes virus entry mediator (HVEM), also known as tumour necrosis factor receptor (TNFR) superfamily 14, regulates a variety of physiological and pathological responses in both innate and acquired immunity. Although HVEM is also suggested to be a critical regulator in tumours, ac...

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Veröffentlicht in:	European journal of cancer (1990) 2015-01, Vol.51 (2), p.157-165
Hauptverfasser:	Hokuto, Daisuke, Sho, Masayuki, Yamato, Ichiro, Yasuda, Satoshi, Obara, Shinsaku, Nomi, Takeo, Nakajima, Yoshiyuki
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Carcinoma, Hepatocellular - genetics Carcinoma, Hepatocellular - metabolism Carcinoma, Hepatocellular - pathology CD4-Positive T-Lymphocytes - metabolism CD8-Positive T-Lymphocytes - metabolism Female Follow-Up Studies Gene Expression Regulation, Neoplastic Granzymes - genetics Granzymes - metabolism HCC Hematology, Oncology and Palliative Medicine Herpesvirus Humans HVEM Interferon-gamma - genetics Interferon-gamma - metabolism Leukocyte Common Antigens - metabolism Liver Neoplasms - genetics Liver Neoplasms - metabolism Liver Neoplasms - pathology Lymphatic Metastasis Lymphocytes, Tumor-Infiltrating - metabolism Male Multivariate Analysis Neoplasm Recurrence, Local Neoplasm Staging Perforin - genetics Perforin - metabolism Prognosis Receptors, Tumor Necrosis Factor, Member 14 - genetics Receptors, Tumor Necrosis Factor, Member 14 - metabolism Survival Analysis TIL TNFRSF14 Tumour immunity
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