P38 and JNK signal pathways are involved in the regulation of phlorizin against UVB-induced skin damage

Phlorizin is well known to inhibit sodium/glucose cotransporters in the kidney and intestine for the treatment of diabetes, obesity and stress hyperglycaemia. However, the effects of phlorizin against ultraviolet B (UVB) irradiation and its molecular mechanism are still unknown. We examined the effe...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Experimental dermatology 2015-04, Vol.24 (4), p.275-279
Hauptverfasser:	Zhai, Yimiao, Dang, Yongyan, Gao, Wenke, Zhang, Ye, Xu, Peng, Gu, Jun, Ye, Xiyun
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidants - pharmacology Apoptosis - drug effects Apoptosis - radiation effects Cell Line Cox-2 Cyclooxygenase 2 Inhibitors - pharmacology Humans Inflammation - etiology Inflammation - pathology Inflammation - prevention & control inflammation reactions MAP Kinase Signaling System MAPK Mice Mice, Inbred BALB C Mice, Nude Phlorhizin - pharmacology phlorizin Reactive Oxygen Species - metabolism Skin - drug effects Skin - metabolism Skin Aging - drug effects Skin Aging - physiology Skin Aging - radiation effects Ultraviolet Rays - adverse effects UVB
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!