Development of a sutureless dural substitute from Bombyx mori silk fibroin

Silk solvent casting, electrospinning, and electrogelation techniques were used to create a biodegradable, biocompatible silk fibroin dural substitute. The all-silk system was designed and produced to improve on currently available materials, grafts and tissue sealants used for dural closure in neur...

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Veröffentlicht in:	Journal of biomedical materials research. Part B, Applied biomaterials Applied biomaterials, 2015-04, Vol.103 (3), p.485-494
Hauptverfasser:	Flanagan, Kelly E., Tien, Lee W., Elia, Roberto, Wu, Julian, Kaplan, David
Format:	Artikel
Sprache:	eng
Schlagworte:	Absorbable Implants Adult Animals Biocompatible Materials biodegradable composite Biomedical materials Bombyx Cell Adhesion Cells, Cultured Dermis - cytology Dura Mater dural substitute electrospinning Female Fibroblasts - cytology Fibroins - isolation & purification Guided Tissue Regeneration Humans Materials research Materials science Materials Testing Neurons - cytology Polyethylene Glycols Pressure Rats Silk silk fibroin Solubility Tensile Strength Tissue Scaffolds tissue sealant
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