Activin A immunoexpression as predictor of occult lymph node metastasis and overall survival in oral tongue squamous cell carcinoma

ABSTRACT Background The presence of regional lymph node metastasis has an important impact on clinical management and prognostication of patients with oral tongue squamous cell carcinoma (SCC). Approximately 30% to 50% of patients with oral tongue SCC have regional metastasis at diagnosis, but the l...

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Veröffentlicht in:	Head & neck 2015-04, Vol.37 (4), p.479-486
Hauptverfasser:	Kelner, Natalie, Rodrigues, Priscila Campioni, Bufalino, Andreia, Fonseca, Felipe Paiva, dos Santos-Silva, Alan Roger, Miguel, Marcia Cristina Costa, Pinto, Clóvis Antonio Lopes, Leme, Adriana Franco Paes, Graner, Edgard, Salo, Tuula, Kowalski, Luiz Paulo, Coletta, Ricardo D.
Format:	Artikel
Sprache:	eng
Schlagworte:	activin A Activins - metabolism Aged Carcinoma, Squamous Cell - metabolism Carcinoma, Squamous Cell - mortality carcinoma-associated fibroblast clinicopathological features Female Head and Neck Neoplasms - metabolism Head and Neck Neoplasms - mortality Humans Immunohistochemistry Lymph Node Excision Lymphatic Metastasis Male Middle Aged Neoplasm Invasiveness oral tongue squamous cell carcinoma Prognosis Squamous Cell Carcinoma of Head and Neck Tongue Neoplasms - metabolism Tongue Neoplasms - mortality
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