Tumor-specific overexpression of a novel keratinocyte lipid-binding protein. Identification and characterization of a cloned sequence activated during multistage carcinogenesis in mouse skin

Differential screening of cDNA libraries from chemically induced malignant mouse skin squamous cell carcinomas (SCCs) identified sequences, including one called mal1, that were up-regulated in their expression at both the benign papilloma and the malignant SCC stages during tumor development. The ma...

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Veröffentlicht in:	The Journal of biological chemistry 1993-08, Vol.268 (23), p.17362-17369
Hauptverfasser:	KRIEG, P, FEIL, S, FÜRSTENBERGER, G, BOWDEN, G. T
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Analytical, structural and metabolic biochemistry Animals Base Sequence Binding and carrier proteins Biological and medical sciences Blotting, Southern Carrier Proteins Cell Transformation, Neoplastic Cells, Cultured Cloning, Molecular DNA, Neoplasm Fatty Acid-Binding Proteins Female Fundamental and applied biological sciences. Psychology Keratinocytes - metabolism Keratinocytes - pathology Mice Molecular Sequence Data Multigene Family Neoplasm Proteins - biosynthesis Neoplasm Proteins - genetics Precipitin Tests Protein Biosynthesis Proteins Sequence Homology, Amino Acid Skin Neoplasms - genetics Skin Neoplasms - metabolism
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