Treatment of Patients With Metastatic Melanoma With Autologous Tumor-Infiltrating Lymphocytes and Interleukin 2

Background: Studies of human tumor-infiltrating lymphocytes (TILs) derived from patients with a variety of histologic types of cancer have demonstrated that cellular immune reactions against established malignancy exist in humans. Purpose: We report the results of using autologous TILs plus high-dos...

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Veröffentlicht in:	JNCI : Journal of the National Cancer Institute 1994-08, Vol.86 (15), p.1159-1166
Hauptverfasser:	Rosenberg, Steven A., Yannelli, John R., Yang, James C., Topalian, Suzanne L., Schwartzentruber, Douglas J., Weber, Jeffrey S., Parkinson, David R., Seipp, Claudia A., Einhorn, Jan H., White, Donald E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Cancer Cellular biology Child Combined Modality Therapy - adverse effects Cyclophosphamide - therapeutic use Female Humans Immunity (Disease) Injections, Intravenous Interleukin-2 - adverse effects Interleukin-2 - therapeutic use Lymphocytes, Tumor-Infiltrating - transplantation Male Melanoma - secondary Melanoma - therapy Middle Aged Patients Treatment Outcome Tumor Cells, Cultured
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