The mitochondrial outer membrane protein Mas22p is essential for protein import and viability of yeast

We have cloned the gene encoding the protein Mas22p, which spans the outer membrane of yeast mitochondria. Cells that completely lack Mas22p are inviable. The plasmid-borne MAS22 gene suppresses several defects resulting from the deletion of one or more of the mitochondrial protein import receptors....

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1994-12, Vol.91 (25), p.11973-11977
Hauptverfasser:	Lithgow, T. (Universitat Basel, Basel, Switzerland), Junne, T, Suda, K, Gratzer, S, Schatz, G
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Cell growth Cells Cellular biology Chromosomes, Fungal Cloning, Molecular COMPOSICION QUIMICA COMPOSITION CHIMIQUE DNA, Fungal - metabolism Fungal Proteins - biosynthesis Fungal Proteins - isolation & purification Fungal Proteins - metabolism GENE GENES Genes, Fungal Genetics Imports Intracellular Membranes - metabolism Intracellular Membranes - ultrastructure MEMBRANAS CELULARES MEMBRANE CELLULAIRE Membrane proteins Membrane Proteins - biosynthesis Membrane Proteins - isolation & purification Membrane Proteins - metabolism Membrane Transport Proteins METABOLISME DES PROTEINES METABOLISMO PROTEICO Mitochondria Mitochondria - metabolism Mitochondrial Membrane Transport Proteins MITOCHONDRIE MITOCONDRIA Models, Structural Molecular Sequence Data MUTANT MUTANTES Plasmids Protein precursors Protein Processing, Post-Translational PROTEINAS PROTEINE Proteins Receptors Receptors, Cell Surface Respiration Restriction Mapping SACCHAROMYCES CEREVISIAE Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae - growth & development Saccharomyces cerevisiae - metabolism Saccharomyces cerevisiae Proteins SECUENCIA NUCLEICA Sequence Homology, Amino Acid SEQUENCE NUCLEIQUE VIABILIDAD VIABILITE Yeast Yeasts
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