Identification of repeat sequence heterogeneity at the polymorphic short tandem repeat locus HUMTH01(AATG) sub(n) and reassignment of alleles in population analysis by using a locus-specific allelic ladder

An allelic ladder containing amplified sequences of seven alleles of the polymorphic human tyrosine hydroxylase locus, HUMTH01, was constructed and employed as a standard marker. Sequence analysis of each ladder component indicates that fragments differ by integral multiples of the AATG core repeat...

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Veröffentlicht in:	American journal of human genetics 1993-01, Vol.53 (4), p.953-958
Hauptverfasser:	Puers, C, Hammond, HA, Jin, Li, Caskey, C T, Schumm, J W
Format:	Artikel
Sprache:	eng
Schlagworte:	heterogeneity HUMTH01 locus loci man population genetics repeated sequence tyrosine 3-monooxygenes
Online-Zugang:	Volltext
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