The use of the in vitro toxin binding inhibition (ToBl) test for the estimation of the potency of tetanus toxoid

The in vitro toxin binding inhibition (ToBl) test was used to determine antitoxin responses in mice immunized with tetanus toxoid. The ToBl test showed good correlation with the in vivo toxin neutralization (TN) test in titration of sera of mice immunized with various doses of DPT-Polio, DT-Polio an...

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Veröffentlicht in:	Biologicals 1991, Vol.19 (1), p.23-29
Hauptverfasser:	Hendriksen, C.F.M., van der Gun, J.W., Marsman, F.R., Kreeftenberg, J.G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal Testing Alternatives Animals Bacteriological methods and techniques used in bacteriology Bacteriology Biological and medical sciences Evaluation Studies as Topic Fundamental and applied biological sciences. Psychology Guinea Pigs In Vitro Techniques Lethal Dose 50 Mice Microbiology Neutralization Tests Tetanus Antitoxin - analysis Tetanus Toxin - antagonists & inhibitors Tetanus Toxoid - analysis Tetanus Toxoid - standards Tetanus Toxoid - toxicity
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