Inclusion body myositis and sarcoid myopathy: Coincidental occurrence or associated diseases

Highlights • We report a patient who had sarcoidosis with inclusion body myositis overlap. • Muscle biopsy revealed evidence of both sarcoidosis and inclusion body myositis. • Features of IBM are inclusion bodies, rimmed vacuoles, expression of MHC class I. • Numerous COX-negative fibers and TDP-43...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Neuromuscular disorders : NMD 2015-04, Vol.25 (4), p.297-300
Hauptverfasser:	Sanmaneechai, Oranee, Swenson, Andrea, Gerke, Alicia K, Moore, Steven A, Shy, Michael E
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Comorbidity Humans Inclusion body myositis Male Muscle biopsy Myositis, Inclusion Body - pathology Myositis, Inclusion Body - physiopathology Myositis, Inclusion Body - therapy Neurology Non-caseating granuloma Quadriceps Muscle - pathology Rimmed vacuoles SARCOID myopathy Sarcoidosis Sarcoidosis - pathology Sarcoidosis - physiopathology Sarcoidosis - therapy
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Highlights • We report a patient who had sarcoidosis with inclusion body myositis overlap. • Muscle biopsy revealed evidence of both sarcoidosis and inclusion body myositis. • Features of IBM are inclusion bodies, rimmed vacuoles, expression of MHC class I. • Numerous COX-negative fibers and TDP-43 cytoplasmic aggregates were noted. • Feature of sarcoidosis is multiple non-necrotizing granulomata.
ISSN:	0960-8966 1873-2364
DOI:	10.1016/j.nmd.2014.12.005