Surgical treatment of glottic cancer: retrospective analysis of 192 cases in a multidisciplinary tertiary care centre in Pune, India
A multidisciplinary team approach is required for the preservation of voice and appropriate management of glottic cancer. This study aimed to investigate the outcomes of surgically treated glottic cancers of all stages. All aspects of surgical management, such as laser cordectomy, partial laryngecto...
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| Veröffentlicht in: | Journal of laryngology and otology 2015-03, Vol.129 (3), p.261-266 |
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| creator | Kelkar, D S Gandhi, S S Oka, G A |
| description | A multidisciplinary team approach is required for the preservation of voice and appropriate management of glottic cancer. This study aimed to investigate the outcomes of surgically treated glottic cancers of all stages. All aspects of surgical management, such as laser cordectomy, partial laryngectomy, total laryngectomy with voice prosthesis, and salvage laryngectomy, conducted at a single tertiary care institute in India, were reviewed.
A retrospective analysis of hospital records was performed for 192 glottic cancer patients who were surgically treated between 2003 and 2007.
Patients with tumour stages 1 or 2 glottic cancer treated with laser cordectomy had a local control rate of 85 per cent and five-year survival rate of 98.6 per cent. The findings suggest that the number of partial laryngectomies performed for stage 3 tumours is declining. Patients with a tumour stage 3 lesion with a fixed hemilarynx or a tumour stage 4 lesion, treated with total laryngectomy, were found to have a five-year survival rate of 61.6 per cent. Nodal status was significantly associated with five-year survival rate.
Surgery offers a viable five-year survival rate in glottic cancer patients. |
| doi_str_mv | 10.1017/S0022215115000274 |
| format | Article |
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A retrospective analysis of hospital records was performed for 192 glottic cancer patients who were surgically treated between 2003 and 2007.
Patients with tumour stages 1 or 2 glottic cancer treated with laser cordectomy had a local control rate of 85 per cent and five-year survival rate of 98.6 per cent. The findings suggest that the number of partial laryngectomies performed for stage 3 tumours is declining. Patients with a tumour stage 3 lesion with a fixed hemilarynx or a tumour stage 4 lesion, treated with total laryngectomy, were found to have a five-year survival rate of 61.6 per cent. Nodal status was significantly associated with five-year survival rate.
Surgery offers a viable five-year survival rate in glottic cancer patients.</description><identifier>ISSN: 0022-2151</identifier><identifier>EISSN: 1748-5460</identifier><identifier>DOI: 10.1017/S0022215115000274</identifier><identifier>PMID: 25684557</identifier><identifier>CODEN: JLOTAX</identifier><language>eng</language><publisher>Cambridge, UK: Cambridge University Press</publisher><subject>Adult ; Aged ; Biopsy ; Cancer therapies ; Carbon dioxide ; Female ; Glottis - pathology ; Glottis - surgery ; Hospitals ; Humans ; India ; Kaplan-Meier Estimate ; Laryngeal Neoplasms - pathology ; Laryngeal Neoplasms - radiotherapy ; Laryngeal Neoplasms - surgery ; Laryngectomy - methods ; Laser surgery ; Laser Therapy - methods ; Main Articles ; Male ; Middle Aged ; Oncology ; Radiation therapy ; Radiotherapy, Adjuvant - methods ; Research centers ; Retrospective Studies ; Salvage Therapy - methods ; Surgery ; Survival Rate ; Tertiary Care Centers ; Treatment Outcome</subject><ispartof>Journal of laryngology and otology, 2015-03, Vol.129 (3), p.261-266</ispartof><rights>Copyright © JLO (1984) Limited 2015</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c443t-b8c6710ffde9a3afe23b44a99cb38eacb76f3aa2fe7156d51100f7ae7413a133</citedby><cites>FETCH-LOGICAL-c443t-b8c6710ffde9a3afe23b44a99cb38eacb76f3aa2fe7156d51100f7ae7413a133</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.cambridge.org/core/product/identifier/S0022215115000274/type/journal_article$$EHTML$$P50$$Gcambridge$$H</linktohtml><link.rule.ids>164,314,780,784,27924,27925,55628</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25684557$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kelkar, D S</creatorcontrib><creatorcontrib>Gandhi, S S</creatorcontrib><creatorcontrib>Oka, G A</creatorcontrib><title>Surgical treatment of glottic cancer: retrospective analysis of 192 cases in a multidisciplinary tertiary care centre in Pune, India</title><title>Journal of laryngology and otology</title><addtitle>J. Laryngol. Otol</addtitle><description>A multidisciplinary team approach is required for the preservation of voice and appropriate management of glottic cancer. This study aimed to investigate the outcomes of surgically treated glottic cancers of all stages. All aspects of surgical management, such as laser cordectomy, partial laryngectomy, total laryngectomy with voice prosthesis, and salvage laryngectomy, conducted at a single tertiary care institute in India, were reviewed.
A retrospective analysis of hospital records was performed for 192 glottic cancer patients who were surgically treated between 2003 and 2007.
Patients with tumour stages 1 or 2 glottic cancer treated with laser cordectomy had a local control rate of 85 per cent and five-year survival rate of 98.6 per cent. The findings suggest that the number of partial laryngectomies performed for stage 3 tumours is declining. Patients with a tumour stage 3 lesion with a fixed hemilarynx or a tumour stage 4 lesion, treated with total laryngectomy, were found to have a five-year survival rate of 61.6 per cent. Nodal status was significantly associated with five-year survival rate.
Surgery offers a viable five-year survival rate in glottic cancer patients.</description><subject>Adult</subject><subject>Aged</subject><subject>Biopsy</subject><subject>Cancer therapies</subject><subject>Carbon dioxide</subject><subject>Female</subject><subject>Glottis - pathology</subject><subject>Glottis - surgery</subject><subject>Hospitals</subject><subject>Humans</subject><subject>India</subject><subject>Kaplan-Meier Estimate</subject><subject>Laryngeal Neoplasms - pathology</subject><subject>Laryngeal Neoplasms - radiotherapy</subject><subject>Laryngeal Neoplasms - surgery</subject><subject>Laryngectomy - methods</subject><subject>Laser surgery</subject><subject>Laser Therapy - methods</subject><subject>Main Articles</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Oncology</subject><subject>Radiation therapy</subject><subject>Radiotherapy, Adjuvant - methods</subject><subject>Research centers</subject><subject>Retrospective Studies</subject><subject>Salvage Therapy - methods</subject><subject>Surgery</subject><subject>Survival Rate</subject><subject>Tertiary Care Centers</subject><subject>Treatment Outcome</subject><issn>0022-2151</issn><issn>1748-5460</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp1kV1rFTEQhoMo9lj9Ad5IwBsvuppJssmud1KsFgoK7f0ym50cUvbjmGQLvfeHm7VHEcWrGZhn3vl4GXsJ4i0IsO-uhZBSQg1Qi5Ja_YjtwOqmqrURj9luK1db_YQ9S-m2MGCFfMpOZG0aXdd2x75fr3EfHI48R8I80Zz54vl-XHIOjjucHcX3PFKOSzqQy-GOOM443qeQNhJaWahEiYeZI5_WMYchJBcOY5gx3vNMMYctcRiJuzKghMJ-XWc645fzEPA5e-JxTPTiGE_ZzcXHm_PP1dWXT5fnH64qp7XKVd84Y0F4P1CLCj1J1WuNbet61RC63hqvEKUnC7UZyluE8BbJalAISp2yNw-yh7h8WynlbiqL0jjiTMuaOjDGyFYpAwV9_Rd6u6yxnP2TqqWSpjGFggfKleekSL47xDCVWzsQ3eZQ949DpefVUXntJxp-d_yypADqKIpTH8Owpz9m_1f2B5Ppm5U</recordid><startdate>20150301</startdate><enddate>20150301</enddate><creator>Kelkar, D S</creator><creator>Gandhi, S S</creator><creator>Oka, G A</creator><general>Cambridge University Press</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88I</scope><scope>8AF</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>S0X</scope><scope>7X8</scope></search><sort><creationdate>20150301</creationdate><title>Surgical treatment of glottic cancer: retrospective analysis of 192 cases in a multidisciplinary tertiary care centre in Pune, India</title><author>Kelkar, D S ; Gandhi, S S ; Oka, G A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c443t-b8c6710ffde9a3afe23b44a99cb38eacb76f3aa2fe7156d51100f7ae7413a133</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Biopsy</topic><topic>Cancer therapies</topic><topic>Carbon dioxide</topic><topic>Female</topic><topic>Glottis - pathology</topic><topic>Glottis - surgery</topic><topic>Hospitals</topic><topic>Humans</topic><topic>India</topic><topic>Kaplan-Meier Estimate</topic><topic>Laryngeal Neoplasms - pathology</topic><topic>Laryngeal Neoplasms - radiotherapy</topic><topic>Laryngeal Neoplasms - surgery</topic><topic>Laryngectomy - methods</topic><topic>Laser surgery</topic><topic>Laser Therapy - methods</topic><topic>Main Articles</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Oncology</topic><topic>Radiation therapy</topic><topic>Radiotherapy, Adjuvant - methods</topic><topic>Research centers</topic><topic>Retrospective Studies</topic><topic>Salvage Therapy - methods</topic><topic>Surgery</topic><topic>Survival Rate</topic><topic>Tertiary Care Centers</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kelkar, D S</creatorcontrib><creatorcontrib>Gandhi, S S</creatorcontrib><creatorcontrib>Oka, G A</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Neurosciences Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>SIRS Editorial</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of laryngology and otology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kelkar, D S</au><au>Gandhi, S S</au><au>Oka, G A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Surgical treatment of glottic cancer: retrospective analysis of 192 cases in a multidisciplinary tertiary care centre in Pune, India</atitle><jtitle>Journal of laryngology and otology</jtitle><addtitle>J. Laryngol. Otol</addtitle><date>2015-03-01</date><risdate>2015</risdate><volume>129</volume><issue>3</issue><spage>261</spage><epage>266</epage><pages>261-266</pages><issn>0022-2151</issn><eissn>1748-5460</eissn><coden>JLOTAX</coden><abstract>A multidisciplinary team approach is required for the preservation of voice and appropriate management of glottic cancer. This study aimed to investigate the outcomes of surgically treated glottic cancers of all stages. All aspects of surgical management, such as laser cordectomy, partial laryngectomy, total laryngectomy with voice prosthesis, and salvage laryngectomy, conducted at a single tertiary care institute in India, were reviewed.
A retrospective analysis of hospital records was performed for 192 glottic cancer patients who were surgically treated between 2003 and 2007.
Patients with tumour stages 1 or 2 glottic cancer treated with laser cordectomy had a local control rate of 85 per cent and five-year survival rate of 98.6 per cent. The findings suggest that the number of partial laryngectomies performed for stage 3 tumours is declining. Patients with a tumour stage 3 lesion with a fixed hemilarynx or a tumour stage 4 lesion, treated with total laryngectomy, were found to have a five-year survival rate of 61.6 per cent. Nodal status was significantly associated with five-year survival rate.
Surgery offers a viable five-year survival rate in glottic cancer patients.</abstract><cop>Cambridge, UK</cop><pub>Cambridge University Press</pub><pmid>25684557</pmid><doi>10.1017/S0022215115000274</doi><tpages>6</tpages></addata></record> |
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| language | eng |
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| source | MEDLINE; Cambridge University Press Journals Complete |
| subjects | Adult Aged Biopsy Cancer therapies Carbon dioxide Female Glottis - pathology Glottis - surgery Hospitals Humans India Kaplan-Meier Estimate Laryngeal Neoplasms - pathology Laryngeal Neoplasms - radiotherapy Laryngeal Neoplasms - surgery Laryngectomy - methods Laser surgery Laser Therapy - methods Main Articles Male Middle Aged Oncology Radiation therapy Radiotherapy, Adjuvant - methods Research centers Retrospective Studies Salvage Therapy - methods Surgery Survival Rate Tertiary Care Centers Treatment Outcome |
| title | Surgical treatment of glottic cancer: retrospective analysis of 192 cases in a multidisciplinary tertiary care centre in Pune, India |
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