TFIIIC relieves repression of U6 snRNA transcription by chromatin

The U6 small nuclear (sn)RNA gene (SNR6) from the yeast Saccharomyces cerevisiae is transcribed by RNA polymerase III in vivo. This gene is unusual in having a TATA box at position -30, and an essential B-block element located downstream of the T-rich termination signal. The B block is one of the tw...

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Veröffentlicht in:	Nature (London) 1993-04, Vol.362 (6419), p.475-477
Hauptverfasser:	Burnol, A.F, Margottin, F, Huet, J, Almouzni, G, Prioleau, M.N, Mechali, M, Sentenac, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences chromatin Chromatin - drug effects Chromatin - physiology Chromatography, Affinity Fundamental and applied biological sciences. Psychology Gene expression Gene Expression Regulation, Fungal genes Genes, Fungal Genetics Histones - metabolism Histones - pharmacology Molecular and cellular biology Molecular genetics Mutagenesis, Site-Directed Oocytes - physiology Plasmids Polymerase Chain Reaction - methods Restriction Mapping Ribonucleic acid RNA RNA, Small Nuclear - genetics Saccharomyces cerevisiae Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae - metabolism Sequence Deletion transcription (genetics) Transcription Factors - isolation & purification Transcription Factors - metabolism Transcription Factors - pharmacology Transcription Factors, TFIII Transcription, Genetic - drug effects Transcriptional Activation Xenopus Yeasts
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