Cell cycle-associated expression of M sub(2)-type isozyme of pyruvate kinase in proliferating rat thymocytes

During a complete cell cycle of rat thymocytes stimulated by concanavalin A and interleukin 2, the activity and mRNA level of pyruvate kinase reached a maximum (8-12-fold increase) 48 h after stimulation coinciding with the S-phase of the cell cycle. Increases of cellular enzyme activity, pyruvate k...

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Veröffentlicht in:The Journal of biological chemistry 1992-01, Vol.267 (9), p.6421-6424
Hauptverfasser: Netzker, R, Greiner, E, Eigenbrodt, E, Noguchi, T, Tanaka, T, Brand, K
Format: Artikel
Sprache:eng
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