miR-629 Targets TRIM33 to Promote TGFβ/Smad Signaling and Metastatic Phenotypes in ccRCC

Renal cell carcinoma (RCC) is the most common neoplasm of the adult kidney, and clear cell RCC (ccRCC) represents its most common histological subtype. To identify a therapeutic target for ccRCC, miRNA expression signatures from ccRCC clinical specimens were analyzed. miRNA microarray and real-time...

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Veröffentlicht in:	Molecular cancer research 2015-03, Vol.13 (3), p.565-574
Hauptverfasser:	Jingushi, Kentaro, Ueda, Yuko, Kitae, Kaori, Hase, Hiroaki, Egawa, Hiroshi, Ohshio, Ikumi, Kawakami, Ryoji, Kashiwagi, Yuri, Tsukada, Yohei, Kobayashi, Takumi, Nakata, Wataru, Fujita, Kazutoshi, Uemura, Motohide, Nonomura, Norio, Tsujikawa, Kazutake
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Carcinoma, Renal Cell - genetics Carcinoma, Renal Cell - pathology Cell Line, Tumor Female Gene Expression Regulation, Neoplastic Humans Intracellular Signaling Peptides and Proteins - metabolism Kidney Neoplasms - genetics Kidney Neoplasms - pathology Male MicroRNAs - genetics Middle Aged Mitochondrial Proteins - metabolism Neoplasm Metastasis Signal Transduction Transcription Factors - genetics Transforming Growth Factor beta - metabolism
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