Identification and Validation of Long Noncoding RNA Biomarkers in Human Non–Small-Cell Lung Carcinomas

Dysregulation of long noncoding RNAs (lncRNAs) has been regarded as a primary feature of several human cancers. However, the genome-wide expression and functional significance of lncRNAs in non–small-cell lung carcinomas (NSCLC) remains unclear. The aim of this study was to identify novel lncRNAs th...

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Veröffentlicht in:	Journal of thoracic oncology 2015-04, Vol.10 (4), p.645-654
Hauptverfasser:	Yu, Hui, Xu, Qinghua, Liu, Fang, Ye, Xun, Wang, Jialei, Meng, Xia
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Biomarkers, Tumor - biosynthesis Biomarkers, Tumor - genetics Carcinoma, Non-Small-Cell Lung - genetics Carcinoma, Non-Small-Cell Lung - metabolism Carcinoma, Non-Small-Cell Lung - pathology Female Gene expression profiling Gene Expression Regulation, Neoplastic Humans Long noncoding RNA Lung Neoplasms - genetics Lung Neoplasms - metabolism Lung Neoplasms - pathology Male Microarray Middle Aged Non–small-cell lung carcinomas Quantitative real-time PCR Real-Time Polymerase Chain Reaction RNA, Long Noncoding - genetics RNA, Neoplasm - genetics
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