A chondrocyte infiltrated collagen type I/III membrane (MACI® implant) improves cartilage healing in the equine patellofemoral joint model

Summary Autologous chondrocyte implantation (ACI) has improved outcome in long-term studies of joint repair in man. However, ACI requires sutured periosteal flaps to secure the cells, which precludes minimally-invasive implantation, and introduces complications with arthrofibrosis and graft hypertro...

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Veröffentlicht in:	Osteoarthritis and cartilage 2015-04, Vol.23 (4), p.648-660
Hauptverfasser:	Nixon, A.J, Rickey, E, Butler, T.J, Scimeca, M.S, Moran, N, Matthews, G.L
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arthroscopy Autologous chondrocyte implantation Biomechanical Phenomena - physiology Biopsy Cartilage repair Cartilage, Articular - drug effects Cartilage, Articular - physiology Cell Survival Cell Transplantation - methods Cells, Cultured Chondrocytes - pathology Chondrocytes - transplantation Collagen Type I - administration & dosage Collagen Type I - pharmacology Collagen type I/III membrane Collagen Type III - administration & dosage Collagen Type III - pharmacology Disease Models, Animal Equine Glycosaminoglycans - physiology Horses Humans In Vitro Techniques Joint MACI Patellofemoral Joint - injuries Patellofemoral Joint - physiopathology Rheumatology Treatment Outcome Wound Healing - drug effects Wound Healing - physiology
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