Intranasal delivery of deferoxamine reduces spatial memory loss in APP/PS1 mice

Intranasal administration, which bypasses the blood–brain barrier and minimizes systemic exposure, is a non-invasive alternative for targeted drug delivery to the brain. While identification of metal dysregulation in Alzheimer’s brain has led to the development of therapeutic metal-binding agents, t...

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Veröffentlicht in:	Drug delivery and translational research 2012-06, Vol.2 (3), p.160-168
Hauptverfasser:	Hanson, Leah R., Fine, Jared M., Renner, Dan B., Svitak, Aleta L., Burns, Rachel B., Nguyen, Thuhien M., Tuttle, Nathan J., Marti, Dianne L., Panter, S. Scott, Frey, William H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomedical and Life Sciences Biomedicine Pharmaceutical Sciences/Technology Research Article
Online-Zugang:	Volltext
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