Mesenchymal Stem Cells Support Neuronal Fiber Growth in an Organotypic Brain Slice Co-Culture Model

Mesenchymal stem cells (MSCs) have been identified as promising candidates for neuroregenerative cell therapies. However, the impact of different isolation procedures on the functional and regenerative characteristics of MSC populations has not been studied thoroughly. To quantify these differences,...

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Veröffentlicht in:	Stem cells and development 2015-04, Vol.24 (7), p.824-835
Hauptverfasser:	Sygnecka, Katja, Heider, Andreas, Scherf, Nico, Alt, Rüdiger, Franke, Heike, Heine, Claudia
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Brain - cytology Brain - drug effects Brain-Derived Neurotrophic Factor - genetics Brain-Derived Neurotrophic Factor - metabolism Coculture Techniques Culture Media, Conditioned - pharmacology Mesenchymal Stromal Cells - metabolism Mice Mice, Inbred C57BL Nerve Fibers - drug effects Nerve Fibers - metabolism Nerve Fibers - physiology Nerve Regeneration Nestin - genetics Nestin - metabolism Original Research Reports
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