Incorporation of bromodeoxyuridine in glutathione S-transferase-positive hepatocytes during rat multistage hepatocarcinogenesis

Cell proliferation is pivotal to all stages of the carcinogenesis process and is one of the primary characteristics of the promotion stage of cancer development. Both a two-stage model of initiation and promotion for analysis of early preneoplasia and a three-stage initiation-promotion-progression m...

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Veröffentlicht in:	Carcinogenesis (New York) 1994-09, Vol.15 (9), p.1939-1947
Hauptverfasser:	Dragan, Y.P., Hully, J., Crow, R., Mass, M., Pitot, H.C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal tumors. Experimental tumors Animals Biological and medical sciences Bromodeoxyuridine - metabolism Cell Division - drug effects Cocarcinogenesis Diethylnitrosamine Experimental digestive system and abdominal tumors Glutathione Transferase - metabolism Liver - cytology Liver - enzymology Liver - metabolism Liver Neoplasms, Experimental - chemically induced Liver Neoplasms, Experimental - enzymology Liver Neoplasms, Experimental - pathology Male Medical sciences Models, Biological Phenobarbital - toxicity Rats Rats, Inbred F344 Tumors
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