MicroRNA-223 regulates inflammation and brain injury via feedback to NLRP3 inflammasome after intracerebral hemorrhage

•miR-223 could downregulate NLRP3 to inhibit inflammation through caspase-1 and IL-1β.•miR-223 could reduce brain edema and improve neurological functions.•miR-223 represents a novel target reducing the inflammatory response. NLRP3 inflammasome, the multimeric protein complexes involved in the proce...

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