Risk factors for anastomotic leakage after anterior resection for rectal adenocarcinoma
Anastomotic leakage (AL) is an important cause of morbidity after surgery for rectal cancer. to analyze the risk factors associated with anastomotic leakage after anterior resection for rectal adenocarcinoma. We collected data from all the patients who had surgical resection with an anastomosis, for...
Gespeichert in:
| Veröffentlicht in: | Tunisie Medicale 2014-07, Vol.92 (7), p.493-496 |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 496 |
|---|---|
| container_issue | 7 |
| container_start_page | 493 |
| container_title | Tunisie Medicale |
| container_volume | 92 |
| creator | Majbar, Mohammed Anass Elmalki Hadj, Omar Souadka, Amine El Alaoui, Mouna Sabbah, Farid Raiss, Mohamed Hrora, Abdelmalek Ahallat, Mohamed |
| description | Anastomotic leakage (AL) is an important cause of morbidity after surgery for rectal cancer.
to analyze the risk factors associated with anastomotic leakage after anterior resection for rectal adenocarcinoma.
We collected data from all the patients who had surgical resection with an anastomosis, for rectal adenocarcinoma at the Surgical Clinic C (Ibn Sina Hospital, Rabat, Morocco), between January 2001 and December 2010. The associations between variables and anastomotic leakage were studied using univariate and multivariate analysis.
Our study included 130 patients. Anastomotic leakage occurred in 28 patients (21.5%). Univariate and multivariate analysis showed that the rate of anastomotic leakage was significantly higher in patients who received preoperative radiotherapy (34.2% vs. 12 %, p = 0.002 - OR 3.8 - CI 95%: 1.5 - 9.4). There was no significant difference in the rate of AL between patients with or without a protective stoma. In the group of patients with AL, the rate of reoperation was significantly lower in patients with a stoma protection (31.8% vs. 83.3%, p = 0.04).
Radiotherapy is a risk factor for anastomotic leakage. The systematic design of a protective stoma in patients receiving neoadjuvant radiotherapy is advisable to reduce the rate of reoperations associated with AL. |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_1664444773</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1664444773</sourcerecordid><originalsourceid>FETCH-LOGICAL-p126t-3b4e8c4576a9795243393fcb7f274da45d99091c2763a9af26a7505b602676ec3</originalsourceid><addsrcrecordid>eNo1kM1LxDAQxXNQ3GXdf0F69FLId8xRFr9gYUEUj2WaTiRu29QkPfjfW3V9h3kP5jdzeGdkTalktWSCrcg25w-6SFNmFbsgK66MUdzSNXl7DvlYeXAlplz5mCoYIZc4xBJc1SMc4R0r8AV_NssMC5Iwoyshjr8HacnQV9DhGB0kF8Y4wCU599Bn3J58Q17v7152j_X-8PC0u93XE-O61KKVeOOkMhqssYpLIazwrjWeG9mBVJ211DLHjRZgwXMNRlHVasq10ejEhlz__Z1S_Jwxl2YI2WHfw4hxzg3TWi4yRizo1Qmd2wG7ZkphgPTV_JchvgE2YVro</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1664444773</pqid></control><display><type>article</type><title>Risk factors for anastomotic leakage after anterior resection for rectal adenocarcinoma</title><source>MEDLINE</source><source>Alma/SFX Local Collection</source><source>EZB Electronic Journals Library</source><creator>Majbar, Mohammed Anass ; Elmalki Hadj, Omar ; Souadka, Amine ; El Alaoui, Mouna ; Sabbah, Farid ; Raiss, Mohamed ; Hrora, Abdelmalek ; Ahallat, Mohamed</creator><creatorcontrib>Majbar, Mohammed Anass ; Elmalki Hadj, Omar ; Souadka, Amine ; El Alaoui, Mouna ; Sabbah, Farid ; Raiss, Mohamed ; Hrora, Abdelmalek ; Ahallat, Mohamed</creatorcontrib><description>Anastomotic leakage (AL) is an important cause of morbidity after surgery for rectal cancer.
to analyze the risk factors associated with anastomotic leakage after anterior resection for rectal adenocarcinoma.
We collected data from all the patients who had surgical resection with an anastomosis, for rectal adenocarcinoma at the Surgical Clinic C (Ibn Sina Hospital, Rabat, Morocco), between January 2001 and December 2010. The associations between variables and anastomotic leakage were studied using univariate and multivariate analysis.
Our study included 130 patients. Anastomotic leakage occurred in 28 patients (21.5%). Univariate and multivariate analysis showed that the rate of anastomotic leakage was significantly higher in patients who received preoperative radiotherapy (34.2% vs. 12 %, p = 0.002 - OR 3.8 - CI 95%: 1.5 - 9.4). There was no significant difference in the rate of AL between patients with or without a protective stoma. In the group of patients with AL, the rate of reoperation was significantly lower in patients with a stoma protection (31.8% vs. 83.3%, p = 0.04).
Radiotherapy is a risk factor for anastomotic leakage. The systematic design of a protective stoma in patients receiving neoadjuvant radiotherapy is advisable to reduce the rate of reoperations associated with AL.</description><identifier>ISSN: 0041-4131</identifier><identifier>PMID: 25775290</identifier><language>eng</language><publisher>Tunisia</publisher><subject>Adenocarcinoma - surgery ; Adult ; Aged ; Aged, 80 and over ; Anastomotic Leak - epidemiology ; Digestive System Surgical Procedures - methods ; Female ; Humans ; Male ; Middle Aged ; Rectal Neoplasms - surgery ; Risk Factors ; Young Adult</subject><ispartof>Tunisie Medicale, 2014-07, Vol.92 (7), p.493-496</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25775290$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Majbar, Mohammed Anass</creatorcontrib><creatorcontrib>Elmalki Hadj, Omar</creatorcontrib><creatorcontrib>Souadka, Amine</creatorcontrib><creatorcontrib>El Alaoui, Mouna</creatorcontrib><creatorcontrib>Sabbah, Farid</creatorcontrib><creatorcontrib>Raiss, Mohamed</creatorcontrib><creatorcontrib>Hrora, Abdelmalek</creatorcontrib><creatorcontrib>Ahallat, Mohamed</creatorcontrib><title>Risk factors for anastomotic leakage after anterior resection for rectal adenocarcinoma</title><title>Tunisie Medicale</title><addtitle>Tunis Med</addtitle><description>Anastomotic leakage (AL) is an important cause of morbidity after surgery for rectal cancer.
to analyze the risk factors associated with anastomotic leakage after anterior resection for rectal adenocarcinoma.
We collected data from all the patients who had surgical resection with an anastomosis, for rectal adenocarcinoma at the Surgical Clinic C (Ibn Sina Hospital, Rabat, Morocco), between January 2001 and December 2010. The associations between variables and anastomotic leakage were studied using univariate and multivariate analysis.
Our study included 130 patients. Anastomotic leakage occurred in 28 patients (21.5%). Univariate and multivariate analysis showed that the rate of anastomotic leakage was significantly higher in patients who received preoperative radiotherapy (34.2% vs. 12 %, p = 0.002 - OR 3.8 - CI 95%: 1.5 - 9.4). There was no significant difference in the rate of AL between patients with or without a protective stoma. In the group of patients with AL, the rate of reoperation was significantly lower in patients with a stoma protection (31.8% vs. 83.3%, p = 0.04).
Radiotherapy is a risk factor for anastomotic leakage. The systematic design of a protective stoma in patients receiving neoadjuvant radiotherapy is advisable to reduce the rate of reoperations associated with AL.</description><subject>Adenocarcinoma - surgery</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Anastomotic Leak - epidemiology</subject><subject>Digestive System Surgical Procedures - methods</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Rectal Neoplasms - surgery</subject><subject>Risk Factors</subject><subject>Young Adult</subject><issn>0041-4131</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1kM1LxDAQxXNQ3GXdf0F69FLId8xRFr9gYUEUj2WaTiRu29QkPfjfW3V9h3kP5jdzeGdkTalktWSCrcg25w-6SFNmFbsgK66MUdzSNXl7DvlYeXAlplz5mCoYIZc4xBJc1SMc4R0r8AV_NssMC5Iwoyshjr8HacnQV9DhGB0kF8Y4wCU599Bn3J58Q17v7152j_X-8PC0u93XE-O61KKVeOOkMhqssYpLIazwrjWeG9mBVJ211DLHjRZgwXMNRlHVasq10ejEhlz__Z1S_Jwxl2YI2WHfw4hxzg3TWi4yRizo1Qmd2wG7ZkphgPTV_JchvgE2YVro</recordid><startdate>201407</startdate><enddate>201407</enddate><creator>Majbar, Mohammed Anass</creator><creator>Elmalki Hadj, Omar</creator><creator>Souadka, Amine</creator><creator>El Alaoui, Mouna</creator><creator>Sabbah, Farid</creator><creator>Raiss, Mohamed</creator><creator>Hrora, Abdelmalek</creator><creator>Ahallat, Mohamed</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>201407</creationdate><title>Risk factors for anastomotic leakage after anterior resection for rectal adenocarcinoma</title><author>Majbar, Mohammed Anass ; Elmalki Hadj, Omar ; Souadka, Amine ; El Alaoui, Mouna ; Sabbah, Farid ; Raiss, Mohamed ; Hrora, Abdelmalek ; Ahallat, Mohamed</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p126t-3b4e8c4576a9795243393fcb7f274da45d99091c2763a9af26a7505b602676ec3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Adenocarcinoma - surgery</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Anastomotic Leak - epidemiology</topic><topic>Digestive System Surgical Procedures - methods</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Rectal Neoplasms - surgery</topic><topic>Risk Factors</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Majbar, Mohammed Anass</creatorcontrib><creatorcontrib>Elmalki Hadj, Omar</creatorcontrib><creatorcontrib>Souadka, Amine</creatorcontrib><creatorcontrib>El Alaoui, Mouna</creatorcontrib><creatorcontrib>Sabbah, Farid</creatorcontrib><creatorcontrib>Raiss, Mohamed</creatorcontrib><creatorcontrib>Hrora, Abdelmalek</creatorcontrib><creatorcontrib>Ahallat, Mohamed</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Tunisie Medicale</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Majbar, Mohammed Anass</au><au>Elmalki Hadj, Omar</au><au>Souadka, Amine</au><au>El Alaoui, Mouna</au><au>Sabbah, Farid</au><au>Raiss, Mohamed</au><au>Hrora, Abdelmalek</au><au>Ahallat, Mohamed</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Risk factors for anastomotic leakage after anterior resection for rectal adenocarcinoma</atitle><jtitle>Tunisie Medicale</jtitle><addtitle>Tunis Med</addtitle><date>2014-07</date><risdate>2014</risdate><volume>92</volume><issue>7</issue><spage>493</spage><epage>496</epage><pages>493-496</pages><issn>0041-4131</issn><abstract>Anastomotic leakage (AL) is an important cause of morbidity after surgery for rectal cancer.
to analyze the risk factors associated with anastomotic leakage after anterior resection for rectal adenocarcinoma.
We collected data from all the patients who had surgical resection with an anastomosis, for rectal adenocarcinoma at the Surgical Clinic C (Ibn Sina Hospital, Rabat, Morocco), between January 2001 and December 2010. The associations between variables and anastomotic leakage were studied using univariate and multivariate analysis.
Our study included 130 patients. Anastomotic leakage occurred in 28 patients (21.5%). Univariate and multivariate analysis showed that the rate of anastomotic leakage was significantly higher in patients who received preoperative radiotherapy (34.2% vs. 12 %, p = 0.002 - OR 3.8 - CI 95%: 1.5 - 9.4). There was no significant difference in the rate of AL between patients with or without a protective stoma. In the group of patients with AL, the rate of reoperation was significantly lower in patients with a stoma protection (31.8% vs. 83.3%, p = 0.04).
Radiotherapy is a risk factor for anastomotic leakage. The systematic design of a protective stoma in patients receiving neoadjuvant radiotherapy is advisable to reduce the rate of reoperations associated with AL.</abstract><cop>Tunisia</cop><pmid>25775290</pmid><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0041-4131 |
| ispartof | Tunisie Medicale, 2014-07, Vol.92 (7), p.493-496 |
| issn | 0041-4131 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1664444773 |
| source | MEDLINE; Alma/SFX Local Collection; EZB Electronic Journals Library |
| subjects | Adenocarcinoma - surgery Adult Aged Aged, 80 and over Anastomotic Leak - epidemiology Digestive System Surgical Procedures - methods Female Humans Male Middle Aged Rectal Neoplasms - surgery Risk Factors Young Adult |
| title | Risk factors for anastomotic leakage after anterior resection for rectal adenocarcinoma |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-07T18%3A20%3A55IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Risk%20factors%20for%20anastomotic%20leakage%20after%20anterior%20resection%20for%20rectal%20adenocarcinoma&rft.jtitle=Tunisie%20Medicale&rft.au=Majbar,%20Mohammed%20Anass&rft.date=2014-07&rft.volume=92&rft.issue=7&rft.spage=493&rft.epage=496&rft.pages=493-496&rft.issn=0041-4131&rft_id=info:doi/&rft_dat=%3Cproquest_pubme%3E1664444773%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1664444773&rft_id=info:pmid/25775290&rfr_iscdi=true |