Honokiol downregulates Kruppel-like factor 4 expression, attenuates inflammation, and reduces histopathology after spinal cord injury in rats

Randomized experimental study. To investigate the neuroprotective effect of honokiol (HNK) on rats subjected to traumatic spinal cord injury (SCI) and the molecular mechanisms. Inflammation contributes to the secondary injury to the spinal cord. Honokiol has been used as a neuroprotective agent beca...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Spine (Philadelphia, Pa. 1976) Pa. 1976), 2015-03, Vol.40 (6), p.363-368
Hauptverfasser:	Liu, Jia, Zhang, Changmeng, Liu, Zhi, Zhang, Jianzheng, Xiang, Zimin, Sun, Tiansheng
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidants - metabolism Biphenyl Compounds - pharmacology Cytokines - metabolism Down-Regulation - drug effects Female Inflammation - drug therapy Inflammation - pathology Kruppel-Like Transcription Factors - analysis Kruppel-Like Transcription Factors - metabolism Lignans - pharmacology Neuroprotective Agents - pharmacology Rats Rats, Sprague-Dawley Spinal Cord - drug effects Spinal Cord - pathology Spinal Cord Injuries - drug therapy Spinal Cord Injuries - metabolism Spinal Cord Injuries - pathology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!