Glial cell line-derived neurotrophic factor (GDNF), a new neurotrophic factor for motoneurones

GLIAL cell line-derived neurotrophic factor (GDNF) has been postulated to be a specific dopaminergic neurotrophic factor since it selectively enhances the survival of dopaminergic neurones in vitro. We report here that GDNF can also act as a neurotrophic factor for motoneurones. GDNF released by GDN...

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Veröffentlicht in:	Neuroreport 1994-12, Vol.6 (1), p.113-118
Hauptverfasser:	Zurn, A D, Baetge, E E, Hammang, J P, Tan, S A, Aebischer, P
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence Biological and medical sciences Brain-Derived Neurotrophic Factor Cells, Cultured Choline O-Acetyltransferase - metabolism Ciliary Neurotrophic Factor Drug Synergism Fundamental and applied biological sciences. Psychology Glial Cell Line-Derived Neurotrophic Factor Mesencephalon - cytology Mesencephalon - enzymology Molecular Sequence Data Motor control and motor pathways. Reflexes. Control centers of vegetative functions. Vestibular system and equilibration Motor Neurons - drug effects Nerve Growth Factors - pharmacology Nerve Tissue Proteins - genetics Nerve Tissue Proteins - pharmacology Parasympathetic Nervous System - cytology Rats Spinal Cord - cytology Vertebrates: nervous system and sense organs
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