What are residual symptoms in schizophrenia spectrum disorder? Clinical description and 1-year persistence within a naturalistic trial

The aim of this study was to evaluate residual symptoms in patients achieving remission according to the consensus criteria and to analyze their potential influence on the patient’s outcome one year after discharge. In total, 399 patients suffering from a schizophrenia spectrum disorder were evaluat...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:European archives of psychiatry and clinical neuroscience 2015-03, Vol.265 (2), p.107-116
Hauptverfasser: Schennach, Rebecca, Riedel, Michael, Obermeier, Michael, Spellmann, Ilja, Musil, Richard, Jäger, Markus, Schmauss, Max, Laux, Gerd, Pfeiffer, Herbert, Naber, Dieter, Schmidt, Lutz G., Gaebel, Wolfgang, Klosterkötter, Joachim, Heuser, Isabella, Maier, Wolfgang, Lemke, Matthias R., Rüther, Eckart, Klingberg, Stefan, Gastpar, Markus, Möller, Hans-Jürgen
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 116
container_issue 2
container_start_page 107
container_title European archives of psychiatry and clinical neuroscience
container_volume 265
creator Schennach, Rebecca
Riedel, Michael
Obermeier, Michael
Spellmann, Ilja
Musil, Richard
Jäger, Markus
Schmauss, Max
Laux, Gerd
Pfeiffer, Herbert
Naber, Dieter
Schmidt, Lutz G.
Gaebel, Wolfgang
Klosterkötter, Joachim
Heuser, Isabella
Maier, Wolfgang
Lemke, Matthias R.
Rüther, Eckart
Klingberg, Stefan
Gastpar, Markus
Möller, Hans-Jürgen
description The aim of this study was to evaluate residual symptoms in patients achieving remission according to the consensus criteria and to analyze their potential influence on the patient’s outcome one year after discharge. In total, 399 patients suffering from a schizophrenia spectrum disorder were evaluated within a naturalistic study. Remission status was examined using the consensus criteria. Residual symptoms were defined as any symptom present at the time-point of remission following analogous analyses performed in depressed patients. Therefore, a PANSS item with a symptom severity of >1 (= at least borderline mentally ill) was defined to be a residual symptom. Remitters with and without residual symptoms were compared regarding psychopathology, functioning and side effects. In total, 236 patients (59 %) were remitters at discharge with 94 % of them suffering from at least one residual symptom. The most common residual symptoms were blunted affect (49 %), conceptual disorganization (42 %) and social withdrawal (40 %). A significant association was found between the presence of residual symptoms and the severity of side effects ( p  
doi_str_mv 10.1007/s00406-014-0528-2
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1664215109</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1664215109</sourcerecordid><originalsourceid>FETCH-LOGICAL-c475t-cd988d885d74faf535de1119f22d7c1b2aba97c4c755ac8910f399313ea2fa023</originalsourceid><addsrcrecordid>eNqNkU2LFDEQhoMo7rj6A7xIwIuXdqvSSX-cRAa_YGEvisemJkk7WbrTbSrNMv4Af_f2OKuIIOypIPW8bxIeIZ4jvEaA-oIBNFQFoC7AqKZQD8QGdVkWjW7xodhAq6HAstRn4gnzNQCgUfBYnCmjKlQIG_Hz656ypORl8hzcQoPkwzjnaWQZomS7Dz-meZ98DCR59janZZQu8JScT2_kdggx2DXlPNsU5hymKCk6icXBU5KzTxw4-2i9vAl5v3aSjJSXRMN6HqzMKdDwVDzqaWD_7G6eiy_v333efiwurz582r69LKyuTS6sa5vGNY1xte6pN6VxHhHbXilXW9wp2lFbW21rY8g2LUJftm2JpSfVE6jyXLw69c5p-r54zt0Y2PphoOinhTusKq3QILT3QE1TQ6XMEX35D3o9LSmuH_lFrW5MY1YKT5RNE3PyfTenMFI6dAjd0Wd38tmtPrujz-743hd3zctu9O5P4rfAFVAngNdV_ObTX1f_t_UWRZmsUA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1658052585</pqid></control><display><type>article</type><title>What are residual symptoms in schizophrenia spectrum disorder? Clinical description and 1-year persistence within a naturalistic trial</title><source>MEDLINE</source><source>SpringerLink Journals - AutoHoldings</source><creator>Schennach, Rebecca ; Riedel, Michael ; Obermeier, Michael ; Spellmann, Ilja ; Musil, Richard ; Jäger, Markus ; Schmauss, Max ; Laux, Gerd ; Pfeiffer, Herbert ; Naber, Dieter ; Schmidt, Lutz G. ; Gaebel, Wolfgang ; Klosterkötter, Joachim ; Heuser, Isabella ; Maier, Wolfgang ; Lemke, Matthias R. ; Rüther, Eckart ; Klingberg, Stefan ; Gastpar, Markus ; Möller, Hans-Jürgen</creator><creatorcontrib>Schennach, Rebecca ; Riedel, Michael ; Obermeier, Michael ; Spellmann, Ilja ; Musil, Richard ; Jäger, Markus ; Schmauss, Max ; Laux, Gerd ; Pfeiffer, Herbert ; Naber, Dieter ; Schmidt, Lutz G. ; Gaebel, Wolfgang ; Klosterkötter, Joachim ; Heuser, Isabella ; Maier, Wolfgang ; Lemke, Matthias R. ; Rüther, Eckart ; Klingberg, Stefan ; Gastpar, Markus ; Möller, Hans-Jürgen</creatorcontrib><description>The aim of this study was to evaluate residual symptoms in patients achieving remission according to the consensus criteria and to analyze their potential influence on the patient’s outcome one year after discharge. In total, 399 patients suffering from a schizophrenia spectrum disorder were evaluated within a naturalistic study. Remission status was examined using the consensus criteria. Residual symptoms were defined as any symptom present at the time-point of remission following analogous analyses performed in depressed patients. Therefore, a PANSS item with a symptom severity of &gt;1 (= at least borderline mentally ill) was defined to be a residual symptom. Remitters with and without residual symptoms were compared regarding psychopathology, functioning and side effects. In total, 236 patients (59 %) were remitters at discharge with 94 % of them suffering from at least one residual symptom. The most common residual symptoms were blunted affect (49 %), conceptual disorganization (42 %) and social withdrawal (40 %). A significant association was found between the presence of residual symptoms and the severity of side effects ( p  &lt; 0.0001) and functioning ( p  = 0.0003) at discharge as well as between residual symptoms and the risk of relapse and chance of remission one year after discharge. Residual symptoms were highly prevalent in remitted schizophrenia inpatients following the suggested definition. Most residual symptoms were persistent baseline symptoms suggesting an ongoing illness severity. Also, the necessity to re-evaluate the consensus criteria questioning the status of remission in these patients is also pointed out.</description><identifier>ISSN: 0940-1334</identifier><identifier>EISSN: 1433-8491</identifier><identifier>DOI: 10.1007/s00406-014-0528-2</identifier><identifier>PMID: 25261210</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Adult ; Analysis of Variance ; Antipsychotic Agents - therapeutic use ; Diagnostic and Statistical Manual of Mental Disorders ; Female ; Follow-Up Studies ; Humans ; Male ; Medicine ; Medicine &amp; Public Health ; Middle Aged ; Neurosciences ; Original Paper ; Psychiatric Status Rating Scales ; Psychiatry ; Psychopathology ; Psychotic Disorders - complications ; Psychotic Disorders - diagnosis ; Psychotic Disorders - drug therapy ; Recurrence ; Retrospective Studies ; Schizophrenia - complications ; Schizophrenia - diagnosis ; Schizophrenia - drug therapy ; Schizophrenic Psychology</subject><ispartof>European archives of psychiatry and clinical neuroscience, 2015-03, Vol.265 (2), p.107-116</ispartof><rights>Springer-Verlag Berlin Heidelberg 2014</rights><rights>Springer-Verlag Berlin Heidelberg 2015</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c475t-cd988d885d74faf535de1119f22d7c1b2aba97c4c755ac8910f399313ea2fa023</citedby><cites>FETCH-LOGICAL-c475t-cd988d885d74faf535de1119f22d7c1b2aba97c4c755ac8910f399313ea2fa023</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00406-014-0528-2$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00406-014-0528-2$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25261210$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Schennach, Rebecca</creatorcontrib><creatorcontrib>Riedel, Michael</creatorcontrib><creatorcontrib>Obermeier, Michael</creatorcontrib><creatorcontrib>Spellmann, Ilja</creatorcontrib><creatorcontrib>Musil, Richard</creatorcontrib><creatorcontrib>Jäger, Markus</creatorcontrib><creatorcontrib>Schmauss, Max</creatorcontrib><creatorcontrib>Laux, Gerd</creatorcontrib><creatorcontrib>Pfeiffer, Herbert</creatorcontrib><creatorcontrib>Naber, Dieter</creatorcontrib><creatorcontrib>Schmidt, Lutz G.</creatorcontrib><creatorcontrib>Gaebel, Wolfgang</creatorcontrib><creatorcontrib>Klosterkötter, Joachim</creatorcontrib><creatorcontrib>Heuser, Isabella</creatorcontrib><creatorcontrib>Maier, Wolfgang</creatorcontrib><creatorcontrib>Lemke, Matthias R.</creatorcontrib><creatorcontrib>Rüther, Eckart</creatorcontrib><creatorcontrib>Klingberg, Stefan</creatorcontrib><creatorcontrib>Gastpar, Markus</creatorcontrib><creatorcontrib>Möller, Hans-Jürgen</creatorcontrib><title>What are residual symptoms in schizophrenia spectrum disorder? Clinical description and 1-year persistence within a naturalistic trial</title><title>European archives of psychiatry and clinical neuroscience</title><addtitle>Eur Arch Psychiatry Clin Neurosci</addtitle><addtitle>Eur Arch Psychiatry Clin Neurosci</addtitle><description>The aim of this study was to evaluate residual symptoms in patients achieving remission according to the consensus criteria and to analyze their potential influence on the patient’s outcome one year after discharge. In total, 399 patients suffering from a schizophrenia spectrum disorder were evaluated within a naturalistic study. Remission status was examined using the consensus criteria. Residual symptoms were defined as any symptom present at the time-point of remission following analogous analyses performed in depressed patients. Therefore, a PANSS item with a symptom severity of &gt;1 (= at least borderline mentally ill) was defined to be a residual symptom. Remitters with and without residual symptoms were compared regarding psychopathology, functioning and side effects. In total, 236 patients (59 %) were remitters at discharge with 94 % of them suffering from at least one residual symptom. The most common residual symptoms were blunted affect (49 %), conceptual disorganization (42 %) and social withdrawal (40 %). A significant association was found between the presence of residual symptoms and the severity of side effects ( p  &lt; 0.0001) and functioning ( p  = 0.0003) at discharge as well as between residual symptoms and the risk of relapse and chance of remission one year after discharge. Residual symptoms were highly prevalent in remitted schizophrenia inpatients following the suggested definition. Most residual symptoms were persistent baseline symptoms suggesting an ongoing illness severity. Also, the necessity to re-evaluate the consensus criteria questioning the status of remission in these patients is also pointed out.</description><subject>Adult</subject><subject>Analysis of Variance</subject><subject>Antipsychotic Agents - therapeutic use</subject><subject>Diagnostic and Statistical Manual of Mental Disorders</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine &amp; Public Health</subject><subject>Middle Aged</subject><subject>Neurosciences</subject><subject>Original Paper</subject><subject>Psychiatric Status Rating Scales</subject><subject>Psychiatry</subject><subject>Psychopathology</subject><subject>Psychotic Disorders - complications</subject><subject>Psychotic Disorders - diagnosis</subject><subject>Psychotic Disorders - drug therapy</subject><subject>Recurrence</subject><subject>Retrospective Studies</subject><subject>Schizophrenia - complications</subject><subject>Schizophrenia - diagnosis</subject><subject>Schizophrenia - drug therapy</subject><subject>Schizophrenic Psychology</subject><issn>0940-1334</issn><issn>1433-8491</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqNkU2LFDEQhoMo7rj6A7xIwIuXdqvSSX-cRAa_YGEvisemJkk7WbrTbSrNMv4Af_f2OKuIIOypIPW8bxIeIZ4jvEaA-oIBNFQFoC7AqKZQD8QGdVkWjW7xodhAq6HAstRn4gnzNQCgUfBYnCmjKlQIG_Hz656ypORl8hzcQoPkwzjnaWQZomS7Dz-meZ98DCR59janZZQu8JScT2_kdggx2DXlPNsU5hymKCk6icXBU5KzTxw4-2i9vAl5v3aSjJSXRMN6HqzMKdDwVDzqaWD_7G6eiy_v333efiwurz582r69LKyuTS6sa5vGNY1xte6pN6VxHhHbXilXW9wp2lFbW21rY8g2LUJftm2JpSfVE6jyXLw69c5p-r54zt0Y2PphoOinhTusKq3QILT3QE1TQ6XMEX35D3o9LSmuH_lFrW5MY1YKT5RNE3PyfTenMFI6dAjd0Wd38tmtPrujz-743hd3zctu9O5P4rfAFVAngNdV_ObTX1f_t_UWRZmsUA</recordid><startdate>20150301</startdate><enddate>20150301</enddate><creator>Schennach, Rebecca</creator><creator>Riedel, Michael</creator><creator>Obermeier, Michael</creator><creator>Spellmann, Ilja</creator><creator>Musil, Richard</creator><creator>Jäger, Markus</creator><creator>Schmauss, Max</creator><creator>Laux, Gerd</creator><creator>Pfeiffer, Herbert</creator><creator>Naber, Dieter</creator><creator>Schmidt, Lutz G.</creator><creator>Gaebel, Wolfgang</creator><creator>Klosterkötter, Joachim</creator><creator>Heuser, Isabella</creator><creator>Maier, Wolfgang</creator><creator>Lemke, Matthias R.</creator><creator>Rüther, Eckart</creator><creator>Klingberg, Stefan</creator><creator>Gastpar, Markus</creator><creator>Möller, Hans-Jürgen</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20150301</creationdate><title>What are residual symptoms in schizophrenia spectrum disorder? Clinical description and 1-year persistence within a naturalistic trial</title><author>Schennach, Rebecca ; Riedel, Michael ; Obermeier, Michael ; Spellmann, Ilja ; Musil, Richard ; Jäger, Markus ; Schmauss, Max ; Laux, Gerd ; Pfeiffer, Herbert ; Naber, Dieter ; Schmidt, Lutz G. ; Gaebel, Wolfgang ; Klosterkötter, Joachim ; Heuser, Isabella ; Maier, Wolfgang ; Lemke, Matthias R. ; Rüther, Eckart ; Klingberg, Stefan ; Gastpar, Markus ; Möller, Hans-Jürgen</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c475t-cd988d885d74faf535de1119f22d7c1b2aba97c4c755ac8910f399313ea2fa023</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Adult</topic><topic>Analysis of Variance</topic><topic>Antipsychotic Agents - therapeutic use</topic><topic>Diagnostic and Statistical Manual of Mental Disorders</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine &amp; Public Health</topic><topic>Middle Aged</topic><topic>Neurosciences</topic><topic>Original Paper</topic><topic>Psychiatric Status Rating Scales</topic><topic>Psychiatry</topic><topic>Psychopathology</topic><topic>Psychotic Disorders - complications</topic><topic>Psychotic Disorders - diagnosis</topic><topic>Psychotic Disorders - drug therapy</topic><topic>Recurrence</topic><topic>Retrospective Studies</topic><topic>Schizophrenia - complications</topic><topic>Schizophrenia - diagnosis</topic><topic>Schizophrenia - drug therapy</topic><topic>Schizophrenic Psychology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Schennach, Rebecca</creatorcontrib><creatorcontrib>Riedel, Michael</creatorcontrib><creatorcontrib>Obermeier, Michael</creatorcontrib><creatorcontrib>Spellmann, Ilja</creatorcontrib><creatorcontrib>Musil, Richard</creatorcontrib><creatorcontrib>Jäger, Markus</creatorcontrib><creatorcontrib>Schmauss, Max</creatorcontrib><creatorcontrib>Laux, Gerd</creatorcontrib><creatorcontrib>Pfeiffer, Herbert</creatorcontrib><creatorcontrib>Naber, Dieter</creatorcontrib><creatorcontrib>Schmidt, Lutz G.</creatorcontrib><creatorcontrib>Gaebel, Wolfgang</creatorcontrib><creatorcontrib>Klosterkötter, Joachim</creatorcontrib><creatorcontrib>Heuser, Isabella</creatorcontrib><creatorcontrib>Maier, Wolfgang</creatorcontrib><creatorcontrib>Lemke, Matthias R.</creatorcontrib><creatorcontrib>Rüther, Eckart</creatorcontrib><creatorcontrib>Klingberg, Stefan</creatorcontrib><creatorcontrib>Gastpar, Markus</creatorcontrib><creatorcontrib>Möller, Hans-Jürgen</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Neurosciences Abstracts</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest Psychology</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>European archives of psychiatry and clinical neuroscience</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Schennach, Rebecca</au><au>Riedel, Michael</au><au>Obermeier, Michael</au><au>Spellmann, Ilja</au><au>Musil, Richard</au><au>Jäger, Markus</au><au>Schmauss, Max</au><au>Laux, Gerd</au><au>Pfeiffer, Herbert</au><au>Naber, Dieter</au><au>Schmidt, Lutz G.</au><au>Gaebel, Wolfgang</au><au>Klosterkötter, Joachim</au><au>Heuser, Isabella</au><au>Maier, Wolfgang</au><au>Lemke, Matthias R.</au><au>Rüther, Eckart</au><au>Klingberg, Stefan</au><au>Gastpar, Markus</au><au>Möller, Hans-Jürgen</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>What are residual symptoms in schizophrenia spectrum disorder? Clinical description and 1-year persistence within a naturalistic trial</atitle><jtitle>European archives of psychiatry and clinical neuroscience</jtitle><stitle>Eur Arch Psychiatry Clin Neurosci</stitle><addtitle>Eur Arch Psychiatry Clin Neurosci</addtitle><date>2015-03-01</date><risdate>2015</risdate><volume>265</volume><issue>2</issue><spage>107</spage><epage>116</epage><pages>107-116</pages><issn>0940-1334</issn><eissn>1433-8491</eissn><abstract>The aim of this study was to evaluate residual symptoms in patients achieving remission according to the consensus criteria and to analyze their potential influence on the patient’s outcome one year after discharge. In total, 399 patients suffering from a schizophrenia spectrum disorder were evaluated within a naturalistic study. Remission status was examined using the consensus criteria. Residual symptoms were defined as any symptom present at the time-point of remission following analogous analyses performed in depressed patients. Therefore, a PANSS item with a symptom severity of &gt;1 (= at least borderline mentally ill) was defined to be a residual symptom. Remitters with and without residual symptoms were compared regarding psychopathology, functioning and side effects. In total, 236 patients (59 %) were remitters at discharge with 94 % of them suffering from at least one residual symptom. The most common residual symptoms were blunted affect (49 %), conceptual disorganization (42 %) and social withdrawal (40 %). A significant association was found between the presence of residual symptoms and the severity of side effects ( p  &lt; 0.0001) and functioning ( p  = 0.0003) at discharge as well as between residual symptoms and the risk of relapse and chance of remission one year after discharge. Residual symptoms were highly prevalent in remitted schizophrenia inpatients following the suggested definition. Most residual symptoms were persistent baseline symptoms suggesting an ongoing illness severity. Also, the necessity to re-evaluate the consensus criteria questioning the status of remission in these patients is also pointed out.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>25261210</pmid><doi>10.1007/s00406-014-0528-2</doi><tpages>10</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0940-1334
ispartof European archives of psychiatry and clinical neuroscience, 2015-03, Vol.265 (2), p.107-116
issn 0940-1334
1433-8491
language eng
recordid cdi_proquest_miscellaneous_1664215109
source MEDLINE; SpringerLink Journals - AutoHoldings
subjects Adult
Analysis of Variance
Antipsychotic Agents - therapeutic use
Diagnostic and Statistical Manual of Mental Disorders
Female
Follow-Up Studies
Humans
Male
Medicine
Medicine & Public Health
Middle Aged
Neurosciences
Original Paper
Psychiatric Status Rating Scales
Psychiatry
Psychopathology
Psychotic Disorders - complications
Psychotic Disorders - diagnosis
Psychotic Disorders - drug therapy
Recurrence
Retrospective Studies
Schizophrenia - complications
Schizophrenia - diagnosis
Schizophrenia - drug therapy
Schizophrenic Psychology
title What are residual symptoms in schizophrenia spectrum disorder? Clinical description and 1-year persistence within a naturalistic trial
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-04T04%3A45%3A09IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=What%20are%20residual%20symptoms%20in%20schizophrenia%20spectrum%20disorder?%20Clinical%20description%20and%201-year%20persistence%20within%20a%20naturalistic%20trial&rft.jtitle=European%20archives%20of%20psychiatry%20and%20clinical%20neuroscience&rft.au=Schennach,%20Rebecca&rft.date=2015-03-01&rft.volume=265&rft.issue=2&rft.spage=107&rft.epage=116&rft.pages=107-116&rft.issn=0940-1334&rft.eissn=1433-8491&rft_id=info:doi/10.1007/s00406-014-0528-2&rft_dat=%3Cproquest_cross%3E1664215109%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1658052585&rft_id=info:pmid/25261210&rfr_iscdi=true