A bioinspired omniphobic surface coating on medical devices prevents thrombosis and biofouling

A non-stick surface coating makes medical devices anti-thrombogenic and resistant to biofilm growth. Thrombosis and biofouling of extracorporeal circuits and indwelling medical devices cause significant morbidity and mortality worldwide. We apply a bioinspired, omniphobic coating to tubing and cathe...

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Veröffentlicht in:	Nature biotechnology 2014-11, Vol.32 (11), p.1134-1140
Hauptverfasser:	Leslie, Daniel C, Waterhouse, Anna, Berthet, Julia B, Valentin, Thomas M, Watters, Alexander L, Jain, Abhishek, Kim, Philseok, Hatton, Benjamin D, Nedder, Arthur, Donovan, Kathryn, Super, Elana H, Howell, Caitlin, Johnson, Christopher P, Vu, Thy L, Bolgen, Dana E, Rifai, Sami, Hansen, Anne R, Aizenberg, Michael, Super, Michael, Aizenberg, Joanna, Ingber, Donald E
Format:	Artikel
Sprache:	eng
Schlagworte:	101/28 13/62 14/34 631/61/54/989 639/301/54/990 639/638/542/967 64 692/699/75/567 96/63 Adhesion Agriculture Animals Anticoagulants Antimicrobial agents Biofilms Biofilms - drug effects Biofouling Biofouling - prevention & control Bioinformatics Biomedical Engineering/Biotechnology Biomedical materials Biomedicine Biotechnology Blood clot Blood clots Catheters - microbiology Coated Materials, Biocompatible - therapeutic use Coatings Equipment and Supplies - microbiology Humans Life Sciences Medical equipment Morbidity Mortality Perfluorocarbons Physiological apparatus Prevention Safety and security measures Surface Properties Swine Thromboembolism Thrombosis Thrombosis - prevention & control
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