Nonstructural Protein sigma 1s Mediates Reovirus-Induced Cell Cycle Arrest and Apoptosis

Reovirus nonstructural protein sigma 1s is implicated in cell cycle arrest at the G2/M boundary and induction of apoptosis. However, the contribution of sigma 1s to these effects in an otherwise isogenic viral background has not been defined. To evaluate the role of sigma 1s in cell cycle arrest and...

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Veröffentlicht in:	Journal of virology 2013-12, Vol.87 (23), p.12967-12979
Hauptverfasser:	Boehme, Karl W, Hammer, Katharina, Tollefson, William C, Konopka-Anstadt, Jennifer L, Kobayashi, Takeshi, Dermody, Terence S
Format:	Artikel
Sprache:	eng
Schlagworte:	Reovirus
Online-Zugang:	Volltext
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