Association of neural tube defects in children of mothers with MTHFR 677TT genotype and abnormal carbohydrate metabolism risk: a case-control study

Abnormalities in maternal folate and carbohydrate metabolism have both been shown to induce neural tube defects (NTD) in humans and animal models. However, the relationship between these two factors in the development of NTDs remains unclear. Data from mothers of children with spina bifida seen at t...

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Veröffentlicht in:	Genetics and molecular research 2014-03, Vol.13 (1), p.2200-2207
Hauptverfasser:	Cadenas-Benitez, N M, Yanes-Sosa, F, Gonzalez-Meneses, A, Cerrillos, L, Acosta, D, Praena-Fernandez, J M, Neth, O, Gomez de Terreros, I, Ybot-González, P
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Alleles Carbohydrate Metabolism Case-Control Studies Female Genetic Association Studies Genotype Homocysteine - blood Humans Incidence Methylenetetrahydrofolate Reductase (NADPH2) - genetics Mothers Neural Tube Defects - epidemiology Neural Tube Defects - genetics Neural Tube Defects - metabolism Polymorphism, Single Nucleotide Pregnancy Risk Factors Spinal Dysraphism - epidemiology Spinal Dysraphism - genetics Spinal Dysraphism - metabolism Young Adult
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