LGALS3BP, lectin galactoside-binding soluble 3 binding protein, promotes oncogenic cellular events impeded by antibody intervention

The extracellular matrix protein lectin galactoside-binding soluble 3 binding protein (LGALS3BP) constitutes a negative prognostic marker of cancer onset and progression with increasing value in clinical application. Since its discovery, however, although the glycoprotein has been implicated in a gr...

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Veröffentlicht in:	Oncogene 2015-01, Vol.34 (1), p.39-52
Hauptverfasser:	Stampolidis, P, Ullrich, A, Iacobelli, S
Format:	Artikel
Sprache:	eng
Schlagworte:	631/67/1059 631/80/79 631/80/86 692/420/755 AKT protein Antibodies - chemistry Antigens, Neoplasm - metabolism Apoptosis Binding proteins Binding sites Biomarkers, Tumor - metabolism Carcinogenesis Carrier Proteins - metabolism Cell Adhesion Cell Biology Cell Line, Tumor Cell Movement Cell Proliferation Cell Survival Cell viability Disease Progression Extracellular matrix Flow Cytometry Gene Expression Regulation, Neoplastic Genetic aspects Glycoproteins - metabolism Human Genetics Humans Immune response Integrins Integrins - metabolism Internal Medicine Lectins Ligands Matrix protein Medicine Medicine & Public Health Oncology original-article Properties Protein Binding Proteins Raf protein Signal Transduction
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